Week10 GU , Diuretics , F/E ch28,29,34,35 Flashcards
(45 cards)
The emergency department (ED) nurse is caring for a patient who is experiencing pulmonary edema. patient is treated with furosemide (Lasix). What will the nurse monitor?
a.Sodium levels
b.Bone narrow function
c.Calcium levels
d.Potassium levels
d.Potassium levels
Furosemide is associated with loss of potassium, so that the patient will need to be monitored carefully for low potassium levels, which could cause cardiac arrhythmias and further aggravate pulmonary edema. The nurse would not monitor sodium or calcium levels or bone marrow function because of the effects of the drug during the acute treatment of pulmonary edema.
The nurse on the coronary unit is caring for a patient with known coronary artery disease who is being treated with cholestyramine (Questran) and hydrochlorothiazide
(HydroDIURIL). What action will the nurse take?
A) Call the physician and refuse to give the drugs without further orders.
B) Make sure that the drugs are given at least 2 hours apart.
C) Give the patient an antacid with the drugs.
D) Check the patient’s blood glucose level before giving the drugs.
B) Make sure that the drugs are given at least 2 hours apart.
The pharmacology instructor is discussing diuretic drugs with the nursing class. What would the instructor cite as an adverse effect of loop diuretics?
A) Hyperkalemia
B. Alkalosis
C. Hypertension
D. Hypercalcemia
B. Alkalosis
Alkalosis is a drop in serum pH to an alkaline state due to bicarbonate loss in urine. Hypokalemia, hypocalcemia, and hypotension are also adverse effect of these drugs. Therefore, the other options are not correct.
A 68-year-old patient, who has type 1 diabetes, is to receive hydrochlorothiazide (HydroDIURIL). Before administration of this medication, what information is most important for the nurse to communicate to the patient?
A) His or her insulin dose may need to be increased.
B) His or he insulin dose may need to be decreased.
C) He or she will need to have him or her urine checked for ketones four times a day.
D) He or she will need to have a creatinine clearance done once a month.
A) His or her insulin dose may need to be increased.
When evaluating an 82-year-old patient receiving hydrochlorothiazide (HydroDIURIL), what laboratory value deviations may be related to the medication?
A) Elevated uric acid levels
B) Reduced blood urea nitrogen (BUN) levels
C) A serum potassium level of 4.7 mEq/L
D) A hemoglobin A1C of 4.8
A) Elevated uric acid levels
Uric acid excretion is decreased because thiazides interfere with its secretory mechanism. High levels of uric acid can result in a condition called gout. Hydrochlorothiazide does not reduce BUN levels. Thiazide diuretics may lead to hypokalemia and increase blood glucose levels. The potassium and hemoglobin A1C levels are normal and not affected by the medication.
The nurse is providing discharge instruction to a patient who has just begun using diuretics. The nurse counsels the patient that it is most important to monitor the intake of foods that contain which element?
A) Calcium
B) Potassium
B) Potassium
Potassium is the most important element to monitor in the diet because diuretics are most likely to lead to hyper- or hypokalemia depending on the diuretic prescribed. Calcium, glucose, and magnesium may need to be monitored in the diet but potassium would be the most important.
The nurse is talking with a group of nursing students. What drug would the nurse tell them, when combined with furosemide (Lasix), is likely to cause hearing loss?
A) Codeine
B) Ciprofloxacin (Cipro)
C) Digoxin (Lanoxin)
D) Gentamicin (Garamycin)
D) Gentamicin (Garamycin)
The risk of ototoxicity increases if loop diuretics are combined with aminoglycoside antibiotics (gentamicin) or cisplatin. No known increased risk of ototoxicity exists when furosemide is taken with codeine, ciprofloxacin, or digoxin.
A student asks the pharmacy instructor what the difference is between the diuretics spironolactone (Aldactone) and furosemide (Lasix). What would the instructor reply?
A) Potassium losses are lower with spironolactone.
B) Potassium losses are greater with spironolactone.
C) Water losses are greater with spironolactone.
D) Sodium losses are greater with spironolactone.
A) Potassium losses are lower with spironolactone.
Spironolactone is a potassium sparing diuretic; therefore, it promotes retention of potassium. Furosemide promotes greater water, sodium, and potassium losses than spironolactone.
The nurse is caring for a patient with a severe head injury. An osmotic diuretic is ordered. The nurse understands which drug is an osmotic diuretic?
A) Spironolactone (Aldactone)
B) Bumetanide (Bumex)
C) Mannitol (Osmitrol)
D) Ethacrynic (Edecrin)
C) Mannitol (Osmitrol)
Mannitol is an osmotic diuretic. Spironolactone is a potassium sparing diuretic. Bumetanide and ethacrynic are loop diuretics.
The staff educator in the ICU is talking with a group of new nurses about osmotic diuretics. The educator would tell the new nurses that osmotic diuretics act on which site in the nephron?
A) Proximal tubule
B) Glomerulus
C) Ascending limb of loop of Henle
D) Collecting tubule
B) Glomerulus
These drugs are freely filtered at the renal glomerulus, poorly reabsorbed by the renal tubule, not secreted by the tubule, and resistant to metabolism.
A 91-year-old patient is being discharged on the diuretic spironolactone (Aldactone). What is the major adverse effect of this type of medication?
A) Hypokalemia
B) Hyperkalemia
C) Gastric irritation
D) Hypertension
B) Hyperkalemia
The most common adverse effect of potassium-sparing diuretics is hyperkalemia, which can cause lethargy, confusion, ataxia, muscle cramps, and cardiac arrhythmias. Hypokalemia, gastric irritation, and hypertension are not recognized as adverse effects of spironolactone.
The nurse is conducting an admission assessment of a patient who has been prescribed hydrochlorothiazide (HydroDIURIL). Which situation would contraindicate the administration of hydrochlorothiazide (HydroDIURIL)?
A) Allergy to sulfa drugs
B) Allergy to codeine
C) BP 160/96
D) Blood glucose level of 140 mg/dL
A) Allergy to sulfa drugs
Thiazide and thiazide-like diuretics are contraindicated with allergy to thiazides or sulfonamides to prevent hypersensitivity reactions. The other options are not correct.
The nurse is caring for a patient who has just been diagnosed with essential hypertension. The nurse is aware that the health care provider will begin therapy with which classification of diuretics?
A) Loop diuretics
B) Carbonic anhydrous inhibitors
C) Thiazide and thiazide-like diuretics
D) potassium-sparing diuretics
C) Thiazide and thiazide-like diuretics
Thiazides are considered to be mild diuretics compared with the more potent loop diuretics. These agents are the first-line drugs used to manage essential hypertension when drug therapy is needed. Loop and potassium-sparing diuretics and carbonic anhydrous inhibitors would be used in combination with or after the thiazide diuretics are no longer effective.
A female patient has a history of frequent bladder infections. Which classification of diuretic would not be recommended for this patient?
A) Thiazide and thiazide-like diuretics
B) Loop diuretics
C) potassium-sparing diuretics
D) Osmotic diuretics
A) Thiazide and thiazide-like diuretics
Urine is slightly alkalinized when the thiazides or thiazide-like diuretics are used because they block reabsorption of bicarbonate. This effect can cause problems for patients who are susceptible to bladder
A patient has just begun to take a prescribed diuretic. Why would the nurse tell the patient to drink 8 to 10 glasses of water daily (unless it is counterindicated)?
A) To decrease the action of the reninangiotensin cycle
B) To make more concentrated plasma
C) To dilute the urine
D) To avoid rebound edema
D) To avoid rebound edema
Care must be taken when using diuretics to avoid fluid rebound, which is associated with fluid loss. If a patient stops taking in water and takes the diuretic, the result will be a concentrated plasma of smaller volume. The decreased volume is sensed by the nephrons, which activate the renin-angiotensin cycle. When concentrated blood is sensed by the osmotic center in the brain, antidiuretic hormone (ADH) is released to retain water and dilute the blood. The result can be rebound edema as fluid is retained. Drinking 8 to 10 glasses of water will not decrease the action of the renin-angiotensin cycle, or make plasma more concentrated. It may produce urine that is dilute but that is not the reason it is recommended.
A patient has just been prescribed furosemide (Lasix). After reviewing the patient’s medication history, what drug would cause the nurse concern when taken with furosemide (Lasix)?
A) Acetaminophen
B) Ferrous sulfate (Feosol)
C) Naproxen sodium (Naprosyn)
D) Ampicillin
C) Naproxen sodium (Naprosyn)
Naproxen sodium is a nonsteroidal antiinflammatory drug. There may also be a decreased loss of sodium and decreased antihypertensive effects if these drugs are combined with indomethacin, ibuprofen, salicylates, or other nonsteroidal antiinflammatory drugs. The patient receiving this combination should be monitored closely and appropriate dosage adjustments should be made. There is no contraindication to the intercurrent use of acetaminophen, ferrous sulfate, or ampicillin.
A patient who was recently prescribed spironolactone calls the clinic and complains that he is not urinating as much as he did when he first started taking this medication. What would be an appropriate question for the nurse to ask this patient?
A) Are you taking a salicylate?
B) Are you taking acetaminophen?
C) Are you taking ibuprofen?
D) Are you using a lot of salt?
A) Are you taking a salicylate?
The diuretic effect decreases if potassium-sparing diuretics are combined with salicylates. Dosage adjustment may be necessary to achieve therapeutic effects. There is no decrease in effect when spironolactone is combined with acetaminophen, ibuprofen, and increased sodium intake.
The nurse is writing a plan of care for a patient who is taking a diuretic. What would be an appropriate nursing diagnosis for this patient?
A) Impaired urinary elimination
B) Monitor the patient response to the drug
C) Imbalanced nutrition: More than body requirements
D) Risk for fluid volume overload
A) Impaired urinary elimination
Nursing diagnoses related to drug therapy may include impaired urinary elimination related to drug effect. Options B, C, and D would not be appropriate nursing diagnoses.
A patient has been prescribed hydrochlorothiazide (HydroDIURIL) and the nurse is preparing to give the patient discharge instructions. Which adverse effects may this patient experience while taking this medication? (Select all that apply.)
A) Constipation
B) Dizziness
C) Polyphagia
D) Nocturia
E) Muscle Cramps
B) Dizziness
D) Nocturia
E) Muscle Cramps
The adverse effects associated with hydrochlorothiazide are dizziness, vertigo, orthostatic hypotension, nausea, anorexia, vomiting, dry mouth, diarrhea, polyuria, nocturia, muscle cramps, and spasms. The patient would not experience polyphagia (great hunger) and constipation.
The nurse is caring for a patient with edema who has just begun taking a diuretic. What will the nurse use to evaluate the effectiveness of this medication? (Select all that apply.)
A) Daily weight
B) Decrease in edema
C) Increase in blood pressure
D) Increase in urinary output
E) Increase in pulse
A) Daily weight
B) Decrease in edema
D) Increase in urinary output
The nurse has just administered 150 g of mannitol IV to a patient with increased intracranial pressure. What is most important for the nurse to monitor in the hour after administration?
A) Weight of patient
B) Blood pressure of patient
C) Pulse of patient
D) Respiratory rate of patient
B) Blood pressure of patient
The most common and potentially dangerous adverse effect related to an osmotic diuretic is the sudden drop in fluid levels. Mannitol peaks 1 hour after administration, therefore, it would be most important to monitor blood pressure. Weight is the best indicator over time but would not be as effective in indicating a dangerous fluid drop as the blood pressure. Respiratory and pulse rates would also not be as effective as blood pressure in evaluating dangerous fluid drops.
LILLY - DIURETICS
When monitoring a patient who has diabetes and is receiving a carbonic anhydrase inhibitor for edema, the nurse will monitor for which possible adverse effect?
a. Metabolic alkalosis
b. Elevated blood glucose
c. Hyperkalemia
d. Mental alertness
b. Elevated blood glucose
An undesirable effect of carbonic anhydrase inhibitors is that they elevate the blood glucose level and cause glycosuria in diabetic patients. They induce metabolic acidosis, making their effectiveness diminishes in 2 to 4 days. In addition, hypokalemia and drowsiness may occur.
The nurse will monitor a patient for signs and symptoms of hyperkalemia if the patient is taking which of these diuretics?
a. Hydrochlorothiazide (HydroDIURIL)
b. Furosemide (Lasix)
c. Acetazolamide (Diamox)
d. Spironolactone (Aldactone)
d. Spironolactone (Aldactone)
Spironolactone (Aldactone) is a potassium-sparing diuretic, and patients taking this drug must be monitored for signs of hyperkalemia. The other drugs do not cause hyperkalemia but instead cause hypokalemia.
Mannitol (Osmitrol) has been ordered for a patient with acute renal failure. The nurse will administer this drug using which procedure?
a. Intravenously, through a filter
b. By rapid intravenous bolus
c. By mouth in a single morning dose
d. Through a gravity intravenous drip with standard tubing
a. Intravenously, through a filter
Mannitol is administered via intravenous infusion through a filter because of possible crystallization. It is not available in oral form. The other options are incorrect.