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Naplex 2025 > Weight Loss > Flashcards

Weight Loss Flashcards

(40 cards)

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1
Q

What BMI is classifed as being overweight or obese?

A
  • Overweight: BMI 25 - 29.9
  • Obese: BMI > 30
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2
Q

What drugs can cause weight gain?

A
  • Antipsychotics
  • Diabetes Drugs [insulin, sulfons, meglits, thiaz]
  • Divalproex
  • Gabapentin
  • Lithium
  • Mirtazapine
  • TCAs
  • Steroids

Hypothyroidism can

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3
Q

What is the treatment prinicple for weight loss?

A
  • Eat a reduced-calorie meal an > 150 minutes per week of physical activity 3 - 5 different days
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4
Q

What are some OTC medications that can help with wieght loss?

A
  • Bitter Orange
  • Excessive amounts of Caffeine [Guarana, Green Tea Powder]
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5
Q

What are some of the requirements some should have to be able to get a prescription for weight loss?

A
  • BMI > 30 or
  • BMI > 27 with one wieght related issue [Dyslipidemia, HTN, Diabetes]
  • NOT appropriate for those loosing small amounts of weight
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6
Q

When should a weight loss medication be Discontinued?

A
  • If they do not produce 5% weight loss at 12 weeks
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7
Q

What are some drugs that can cause weight loss?

A
  • ADHD Drugs
  • Burpropion
  • GLP-1 Agonist
  • Pramlintide
  • Roflumilast
  • SGLT-2 inhibitors
  • Topiramate
  • Tizepatide

Hyperthyroidism, Celiad Disease, IBS

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8
Q

What is important to know about wieght loss medicatoins and pregnacy?

-

A
  • AVOID all
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9
Q

What is important to know about weight loss medications and Hypertension?

A
  • Avoid: Contrave and Stimulants
  • Caution: Qsymia

Contrave has bupropion
Stimulants [Phentermine] = contraindicated with uncontrolled HTN
Qsymia monitor HR

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10
Q

What is important to know about weight loss medications with Depression?

A
  • Caution in young adults [Contrave has increase suicidal risk]
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11
Q

What is important to know about weight loss medications and Seizures?

A
  • Avoid: Contrave [lowers thershold]
  • Caution: Qsymia [must taper slowly (contains Toperimate)]
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12
Q

What is important to know about Weight loss medications and taking opiods?

A
  • Avoid: Contrave [block opiods receptors (contains Naltrexone)]
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13
Q

What is the Brand Name for Phentermine/Topiramte?

A
  • Qsymia
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14
Q

What is the way that Qsymia works in the body?

A
  • Phentermine: Sympathomimetic (stimulant) that releases NE to decrease appetite
  • Topiramate: Increase satiety (feels fuller) and decreases appetite [affecting GABA?]
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15
Q

What are some of the contraindications for Qsymia?

A
  • Pregnancy [REMS]
  • Glaucoma
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16
Q

What are some of the side effects for Qsymia?

A
  • Tachycardia
  • Insomnia
  • Vision Problems
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17
Q

What are some additional notes about Qsymia?

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A
  • Be sure to Taper off dose [contains Topiramate] due to seizure risk
18
Q

What is the brand name for Naltrexone/ Bupropion?

19
Q

What is the way that Contrave works wihtin the body?

Study These Flashcards
A
  • Naltrexone: decrease food cravings
  • Bupropion: decrease appetite
20
Q

What are some contraindications for contrave used for weight loss?

Study These Flashcards
A
  • Pregnancy
  • Chronic Opioid use
  • Uncontrolled HTN
  • Seizure Disorders
  • Using other bupropion containing products
  • Use of MAOi within 14 days
21
Q

What are some warnings for contrave used for weight loss?

Study These Flashcards
A
  • Use in cautions with psychiartic disorders
22
Q

What are some side effects for contrave used for weight loss?

Study These Flashcards
A
  • N/V/Constipation
  • Headache
  • Dizziness
  • Dry Mouth
  • Insomnia
23
Q

What are some additional notes for contrave used for weight loss?

Study These Flashcards
A
  • Naltrexone blocks opioids - can block pain relief and induce withdrawls (DC opioids or burenorphine 7-14 days before starting contrave)
24
Q

What are the GLP-1 & Dual GLP-1/GIP agonist that are used for weightloss?

Study These Flashcards
A
  • Liraglutide (Saxenda) - Victoza for diabetes
  • Semaglutide (Wegovy) - Ozempic for diabetes
  • Tirazepatide (Zepbound) - Mounjaro for diabetes

GLP-1: Lira and Sema
Dual: Tira

25
What are some **Contraindications** for **GLP-1 Agonits & Dual GLP-1/GIP Agonist** used for **weight loss**?
- Saxenda: pregnancy
26
What are some **warnings** for **GLP-1 Agonist & Dual GLP-1/GIP Agonist** used for **weight loss**?
- **Pancreatitis, Hypoglycemia**, Kidney Injuries - **NOT RECOMMENDED** in those with severe **GI diseases** (gastroparesis)
27
What are some **side effects** for **GLP-1 Agonist & Dual GLP-1/GIP agonist** used for **weight loss**?
- **Nausea**, Vomiting, Diarrhea, Constipation, Hypoglycemia, Injection site reations ## Footnote **MAINLY** GI related stuff
28
29
What is the way that the **GLP-1 Agonist & Dual GLP-1/GIP Agonist** work within the body?
- Increase Satiety (feel fuller longer)
30
What are the **Lipase inhibitors** that are used for **weight loss**?
- Orlistat (Rx - Xenical; OTC - Alli)
31
What is the way that **Orilstat** works in the body for **weight loss**?
- Decresaes absorption of dietary fats by 30%?
32
What are some **contraindications** for **orilstat** used for **weight loss**?
- Pregnancy
33
What are some **side effects** for **orilstat** used for **weight loss**?
- GI (Flatus with discharge, Fatty stools, fecal urgency) ## Footnote Lots of pooping?
34
What are some **additional notes** for **orilstat** used for **weight loss**?
- Take a **multivitamin w/ A, D, E, K and Beta-Carotene** at bedtime or separted by > 2 hours - **MUST** stick to diet
35
What are some **appetite suppressants** that are used for **weight loss**?
- **Phenteramine (Adipex-P)** C-IV - Diethylpropion C-IV - Phendrmietrazine C-III - Benzphetamine C-III
36
What is the way that the **appetite suppressants** work within the body for **weight loss**/
- Sympathomimetics (Stimulants); release Norepi to stimulate satiety = **decrease appetite**
37
What are some **contraindications** for **appetite suppressants** used for **weight loss**?
- Cardio diseases (uncontrolled HTN, Pulmonary HTN, CHF, CAD...) - Hyperthyroidism, Glaucoma, Pregnancy - Hx of Drug Abuse
38
What are some **side effects** for **appetite stimulants** used for **weight loss**?
- Tachycardia - Agitatoin - Increase BP - Pulmonary HTN (if using for < 3 m)
39
What are some things to **monitor** for with **appetite stimulants** used for **weight loss**?
- HR, BP - Symptoms of Pulmonary HTN
40
What are some **Additional notes** for **appetite suppressants** used for **weight loss**?
- Used for **short term**; Up to **12 weeks**

Naplex 2025 (70 decks)

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