Wk (Deliver + Male)

Question 1

Methyl Testosterone is what?

Answer 1

Oral T analog

Question 2

Methyl Testosterone specific SE?

Answer 2

Hepatotoxicity

Question 3

Oxandrolone is what?

Answer 3

Oral DHT analog

Question 4

Oxandrolone use?

Answer 4

Anabolic steroid

Question 5

Male SE of synthetic Androgens?

Answer 5

Gynecomastia
Low Sperm
Baldness

Question 6

Female SE of synthetic Androgens?

Answer 6

Short lighter menses
Clitorus enlargment
Increased body hair

Question 7

Cyproterone Acetate is what?

Answer 7

Androgen R antagonist

Question 8

Flutamide is what?

Answer 8

Pure non-steroidal Androgen R antagonist

Question 9

Bicalutamide is what?

Answer 9

Pure non-steroidal Androgen R antagonist

Question 10

Nilutamide is what?

Answer 10

Pure non-steroidal Androgen R antagonist

Question 11

Cyproterone Acetate Use?

Answer 11

Decreases male libido

Hirsutism in women

Question 12

Pure non-steroidal Androgen R antagonist uses?

Answer 12

Advanced Prostate Cancer

Question 13

SE of Pure non-steroidal Androgen R antagonists?

Answer 13

Gynecomastia

Hepatotoxicity

Question 14

Gonadorelin is what?

Answer 14

GnRH agonist

Question 15

Gonadorelin is administered how?

Answer 15

IV

Question 16

Gonadorelin is used for what? How is it administered?

Answer 16

Pulsatile = Improved sperm count

Question 17

Leuprolide is what?

Answer 17

GnRH R Agonist

Question 18

Leuprolide is used or what? How is it administered?

Answer 18

Non-pulsatile for Medical castration

Question 19

Degarelix is what?

Answer 19

GnRH Antagonist

Question 20

Ganirelix is what?

Answer 20

GnRH Antagonist

Question 21

Cetrorelix is what?

Answer 21

GnRH Antagonist

Question 22

Which GnRH antagonist is used for PBH or Male chemical castration?

Answer 22

Degarelix

Question 23

Which GnRH antagonist(s) are used for Ovulation stimulation?

Answer 23

Ganirelix

Cetrorelix

Question 24

Finasteride is what?

Answer 24

5-a-reductase inhibitor

Question 25

Dutasteride is what?

Answer 25

5-a-reductase inhibitor

Question 26

5-a-reductase inhibitors are used for what?

Answer 26

Male pattern baldness | BPH

Question 27

What drug classes are used for chemical castration in males?

Answer 27

``` Androgen R antagonists GnRH agonists (Non-pulsatile) GnRH antagonists (Non-pulsatile) ```

Question 28

Sildenafil is what?

Answer 28

PD5 inhibitor

Question 29

Sildenafil is used for?

Answer 29

ED

Question 30

What should Sildenafil never be given with?

Answer 30

Nitrates | a-blockers

Question 31

Pitocin is what?

Answer 31

Synthetic Oxytocin

Question 32

Oxytocin receptor signals via what?

Answer 32

Gq GPCR --> IP3

Question 33

Pitocin Use?

Answer 33

Stimulate uterine contractions Decreases post-partum bleeding Milk Let down

Question 34

When don't you use Pitocin?

Answer 34

For Abortion If head to big/pelivs to small If hypertonic contractions

Question 35

PGE vs. PGF in labor?

Answer 35

PGE - softens cervix - Stimulates uterine contractions - Gs signalling PGF - Stimulates uterine contractions - Gq signalling

Question 36

Dinoprostone is what?

Answer 36

Natural PGE

Question 37

Misoprostol is what?

Answer 37

Synthetic PGE

Question 38

Carboprost is what?

Answer 38

Synthetic PGF2

Question 39

Which PG can be used to treat hyatidiform mole formation?

Answer 39

Dinoprostone

Question 40

Which PG can be used with Mifepristone as an abortifacient?

Answer 40

Misoprostol

Question 41

Which PG is Injected IM to to induce labor at ANY TIME DURING PREGNANCY?

Answer 41

Carboprost

Question 42

SE of PGs?

Answer 42

Flu-like

Question 43

Erogts MOA?

Answer 43

Toxin that stimulate SM contraction via a, DA, and 5HT Rs

Question 44

Ergonovine is used for?

Answer 44

Post-partum bleeding

Question 45

Ergotamine is used for?

Answer 45

Migranes

Question 46

Terbutaline is what?

Answer 46

B2 agonist

Question 47

Terbutaline acts via what signalling?

Answer 47

B2 --> Gs --> cAMP --> PKA --> Decreased MLCK --> SM relaxation

Question 48

Terbutaline is used for what?

Answer 48

Reduce contractions

Question 49

Terbutaline SE?

Answer 49

Tachy --> MI Pulm edema Hyperglycemia

Question 50

Magnesium Sulfate MOA?

Answer 50

Binds and blocks L-Ca Channels --> SM relaxation

Question 51

Magnesium Sulfate Use?

Answer 51

Prevent seizures during eclampsia

Question 52

Atosiban is what?

Answer 52

Oxytocin R antagonist

Question 53

Atosiban use?

Answer 53

Delay labor

Question 54

Atosiban good and bad?

Answer 54

``` Good = less SE than terbutaline Bad = Higher infant mrtality ```

Question 55

Indomethacin use?

Answer 55

Inhibits PG stimulation of contractions