WK1

Question 1

Omnitrope is what?

Answer 1

rhGF

Question 2

Nutropin is what?

Answer 2

rhGF

Question 3

Norditropin is what?

Answer 3

rhGF

Question 4

Genotropin is what?

Answer 4

rhGF

Question 5

Siazen is what?

Answer 5

rhGF

Question 6

Mescarin is what?

Answer 6

rhIGF1

Question 7

Mescarin Rinfabate is what?

Answer 7

rhIGF1 + IGF1BP

Question 8

When do you use rhGF?

Answer 8

For hyposecretion of GH
SHOX
Hypopitutarism

Question 9

When do you use rhIGF1?

Answer 9

For Laron Syndome GF problems

Question 10

Why rhIGF1 instead of rhGF?

Answer 10

Because Laron Syndrome is a defect in the GH receptor so recombinant GH won’t work. IGF attenuates well enough

Question 11

SE of rhGF?

Answer 11

Ab production (No consequence)
Scoliosis
Diabetogenic

Question 12

SE of rhIGF1?

Answer 12

Hypoglycemia

CYP induction

Question 13

When shouldn’t you use rIGF?

Answer 13

Cancer

For growth if epiphyseal plates are closed

Question 14

Bromocriptine is what?

Answer 14

DA analog

Question 15

Octreotide is what?

Answer 15

SST analog

Question 16

Pegvisomant is what?

Answer 16

GH antagonist

Question 17

What are treatment options for hypersecretion of GH?

Answer 17

DA analog
SST analog
GH Receptor Antagonist

Question 18

SE of Octreotide?

Answer 18

Diarrhea
Flatulence
Malabsorption

Question 19

SE of Pegvisomant?

Answer 19

Ab formation

Liver Toxicity

Question 20

Cabergoline is what?

Answer 20

DA agonist

Question 21

Cabergoline is most effective for what disease?

Answer 21

Hypersecretion of prolactin

- Shrinks Tumor

Question 22

SE of Cabergoline

Answer 22

Nausea, vomiting, dizziness, hypotension
Stroke
Psych manifestations

Question 23

Levothyroxine is what?

Answer 23

T4 analog

Question 24

Liothyronine is what?

Answer 24

T3 analog

Question 25

Methimazole is what?

Answer 25

Thiamide that blocks Thyroid Peroxidase

Question 26

Carbimazole is what?

Answer 26

Thiamide that blocks Thyroid Peroxidase

Question 27

Propylthiouracil is what?

Answer 27

Thiamide that blocks Thyroid Peroxidase and Deiodinase 1

Question 28

Which Thyroid analog has a longer half life?

Answer 28

Levothyroxine

Question 29

SE of Thyroid Analogs?

Answer 29

Hyperthyroidism symptoms Afib Bone loss

Question 30

SE of Methimazole?

Answer 30

Embryopathy if pregnant

Question 31

SE of propylthiuracil

Answer 31

LIVER TOX

Question 32

Which Thiamide has a longer duration of action?

Answer 32

Methimazole

Question 33

How long until steady state of thyroxine?

Answer 33

6-8wks

Question 34

How long for full effect of Ptopylthiouracil?

Answer 34

2 wks

Question 35

First line treatment for Graves'?

Answer 35

Methimazole

Question 36

Radioactive 131-I used for?

Answer 36

Destruction of thyroid

Question 37

Radioactive 123-I used for?

Answer 37

Thyroid Scan

Question 38

Iodine used for?

Answer 38

Thyroid Storm TX | Prep for thyroidectomy

Question 39

SE of Iodine administration

Answer 39

Allergic Sore Gums and Teeth Excessive Salivation

Question 40

Why would you give Iodine for Thyroid Storm or prep for thyroidectomy?

Answer 40

High levels of Iodine inhibit all aspects of I- metabolism