Wk6 Regulation Of Gene Expression

Question 1

What is an enhancer element?

Answer 1

Regulates transcription, typically cell specific gene activation - both 5’ and 3’

Question 2

What is a promoter element?

Answer 2

Binds gene specific and general transcription factors, regulates RNA polymerase recruitment

Question 3

What is a transcriptional start site?

Answer 3

Transcript starts at +1

Question 4

What are exons?

Answer 4

Expressed sequence, codes for protein sequence and introns

Question 5

What is a terminator?

Answer 5

Tells RNA polymerase to stop producing RNA

Question 6

What is a transcriptional factor?

Answer 6

Can bind to promoters or enhancers

Question 7

What is RNA polymerase?

Answer 7

Sits at start of gene

Question 8

Why could nucleosome assembly create problems for gene regulation?

Answer 8

It may cause issues as it is involved in turning genes on and off - the wrong gene may be switched on

Question 9

What happens with decreased acetylation?

Answer 9

Chromatin condenses, transcriptional machinery cannot access DNA and so it is not transcribed