Flashcards in Wound Heal/inflammation Deck (45):
What are the three types of inflammation ?
Acute- sudden onset
Chronic-always there, slow
What is the first vascular response for acute (injury) inflammation ?
Brief vasoconstriction (for homeostasis )
What happens to blood flow during cellular response of inflammation
Blood flow SLOWS as fluid is lost
During cellular response, which blood cell is first to respond
WBC: neutrophils (within 6-12 hours)
Which cells increase in response to allergic disorders, inflammation of skin & parasitic infections?
Describe acute inflammation Vascular response:
-hyperemia (increased blood)
-increased capillary permeability
What is the adaptive mechanism of inflammation:
-destroy/dilute injurious agent
-prevent further spread of injury
-remove necrotic materials
-establish healing environment
Describe cellular response of inflammation:
-blood flow slows
Which exudate is clear like plasma?
Which exudate is red with many RBCs?
Which exudate is described as pinkish, watery with RBCs?
What is the final phase of healing?
Regeneration & Repair
Definition of Labile
What meds to consider in inflammatory process that can alter response?
Acetylcytic acid, NSAIDS, CoRticosteroids, acetaminophen
What are the local manifestations of inflammation?
-Loss of function
What is the inflammatory response?
A sequential reaction to cell injury that neutralizes and dilutes the inflammatory agent, removes necrotic materials and establishes a suitable environment for healing and repair.
What are some variables that may affect the physiological tolerance to heat and cold?
-Body part, which parts are temperature sensitive?
-size of exposed body part
-length of exposure
-intactness of skin
- neurosensory impairment
-impaired mental status
What factors to primary prevention may interfere with wound healing?
-decreased blood supply
How does a deficiency in Vitamin C effect wound healing?
Delays formation of collagen fibers and capillary development
How can decreased protein levels effect wound healing?
It decreases the supply of amino acids for tissue repair.
An inadequate blood supply has what effect on would healing?
It decreases the supply of nutrients to injured area, decreases removal of exudative debris and inhibits the inflammatory response.
How does anemia effect wound healing?
Decrease in supply of oxygen at the tissue level.
What are sutures and fibrin sealant used for?
To facilitate in wound closure and to create an optimal setting for wound healing.
What is included in the assessment of a wound
-tissue loss, wound margins, exudate
How long does it take to receive the results of a wound culture?
When are early signs of an infection usually evident in primary intention wound healing?
Between the 3rd and 5th days
What are the stages of wound healing?
How long does the granulation phase last in primary intention wounds?
5 days to 3 weeks
What does RICE stand for?
What lab test would be done in a patient with acute inflammation?
Increases SED rate
Bandages are applied how & RAT for this?
Distal to proximal
-aids return of flow of venous blood
What type of WBC increases in the case of a viral infection?
Wound infection; what would leukocytes look like ? (#)
3 complications if primary intention wound healing:
6 subscales of Braden scale
Friction & shear
3 types of debridement
Mechanical: wet-to-dry; irrigation, scrubbing
Enzymatic: drugs used to dissolve necrotic tissue (eg. Collagenese)
How to wrap dressings/ace wrap
Figure 8 toward body ( closest toward heart)
RYB color code;
Full thickness loss, subcutaneous fat visible, slough, tunneling visible
Dressing: semi permeable membrane permits gas exchange. Used for dry non-infected wounds or for minimal drainage
Dressing: does not allow for O2 to I diffuse from wound, supports debridement, light to moderate drainage
Dressing: used to hydrate dry wound & maintain moist healing environment, debridement purposes, partial full thickness, deep wounds with minimal drainage & necrotic wounds
Dressing: non-adhesive pads/ribbons for wounds with moderate to heavy exudate
How does complement system affect healing process?
Mediates and amplifies immune system