Year 2 Pharmacology Flashcards Preview

Question 1

1

Amoxicillin

Answer

beta lactam antibiotic
broad spectrum

Question 2

2

Methicillin

Answer

beta lactam antibiotic
gram positive

Question 3

3

cefuroxime

Answer

transpeptidase inhibitor
broad spectrum antibiotic

Question 4

4

benzylpenicillin

Answer

beta lactam
gram positive

Question 5

5

oxytetracycline

Answer

30s inhibitor
broad spectrum

Question 6

6

erythromycin

Answer

50s inhibitor
broad spectrum

Question 7

7

Gentamycin

Answer

30s/50s inhibitor
aminoglycoside
broad spectrum
oto- and nephro-toxicity

Question 8

8

Rifampicin

Answer

RNA polymerase inhibitor
broad spectrum
TB

Question 9

9

Trimethoprim

Answer

DHF reductase inhibitor
UTI

Question 10

10

Suxamethoxazole

Answer

PABA analogule
UTI

Question 11

11

Vancomycin

Answer

peptidoglycan inhibitor
interferes with cell wall production
drug of last resort

Question 12

12

Collistin

Answer

Polymixin
membrane detergent

Question 13

13

Ciprafloxacin

Answer

broad spectrum
topoisomerase II inhibitor

Question 14

14

Fusidic Acid

Answer

EF-G inhibitor
creams and eye drops

Question 15

15

Aciclovir

Answer

DNA polymerase inhibitor
nucleotide analogue competes with endogenous nucloetide

Question 16

16

Amantidine

Answer

viral ion channle disruptor - this prevents viral uncoating

Question 17

17

Amprenavir

Answer

protease inhibitor

Question 18

18

Phenoxymethylpenicillin

Answer

transpeptidase inhibitor
gram positive

Question 19

19

Zidovudine

Answer

nucloside reverse transcriptase inhibitor

Question 20

20

Clotrimazole

Answer

antifungal
prevents production of ergosterol

Question 21

21

Fluconazole

Answer

antifungal
prevents the production of ergosterol

Question 22

22

Nystatin

Answer

antifungal
binds to ergosterol therefore causes formation of pores

Question 23

23

Amphoteraxcin

Answer

antifungal
binds to ergosterol therefore causes the formation of pores

Question 24

24

Pyrimethamine

Answer

Antimalarial
inhibits DHF reductase
prevents schizoint division

Question 25

25

Quinine

Answer

Antimalarial
Inhibits Haem polymerase; prevents parasite detoxification of blood
also used to treat Crohn's disease (unclear mechanism)

Question 26

26

Artemether

Answer

Antimalarial
results in the formation of oxygen free radicals which damage infected red blood cells

Question 27

27

Griseofulvin

Answer

fungal mitosis inhibitor

Question 28

28

Clobetasone

steroid

Answer

alkylating chemotherapy agent

Answer

alkylating chemotherapy agent

Answer

B cell CD20 antibody
used to treat blood cancers

Answer

anthracycline antibiotic
inhibits topoisomerase II
chemotherapy agent

Answer

microtubule stabilisation agent
prevents mitosis
used to treat advanced ovarian and breast cancers

Answer

competes with endogenous nucleotides for encorporation into DNA
prevents DNA replication

Answer

inhibits topoisomerase II
chemotherapy agent

Answer

tubulin polymerase inhibitor
destabilises the mitotic spindle

Answer

tyrosine kinase inhibitor
used to treat CML

Answer

vitamin A analogue
used to treat skin conditions and promyelocytic leukaemia

Answer

alkylating chemotherapy agent

Answer

inhibits ENaC

Answer

loop diuretic
inhibits NKCC2

Answer

inhibits NCC

Answer

osmotic load diuretic

Answer

alpha-1 adrenoreceptor antagonist

Answer

aldosterone antagonist
potassium sparing diuretic

Answer

inhibits carbonic anhydrase

Answer

barbituate
GABA agonist

Answer

synthetic versions of progesterone
Contraception

Answer

used to induce labour
stimulates uterine contraction

Answer

Prostaglandin E2
used to induce labour

Answer

inhibits purine synthesis
used to treat autoimmune conditions

Answer

selective COX2 inhibitor

Answer

immunosuppressant
used to treat autoimmune conditions (RA, IBD)

Answer

Immunosuppressant; inhibits calcineurin

Answer

Calcitonin preparation
Osteoporosis

Answer

SERM
HRT; osteoporosis

Answer

Bisphosphonate
Osteoporosis

Answer

Inhaled anaesthetic agent

Answer

intravenous anaesthetic

Answer

sodium channel inhibitor
used to treat epilepsy

Answer

sodium channel inhibitor
used to treat epilepsy
not used for absence seizures

Answer

sodium channel inhibitor
used to treat epilepsy

Answer

inhibits GABA transaminase therefore potentiates the action of GABA
epilepsy

Answer

Ca channel inhibitor
absence seizures

Answer

acetycholinesterase inhibitor
alzheimers

Answer

NMDA antagonist (reduces glutamate toxicity)
alzheimer's

Answer

SABA
beta 2 agonist

Answer

LABA
beta 2 agonist

Answer

LABA
beta 2 agonist

Answer

Leukotriene receptor antagonist
asthma

Answer

anticholinergic bronchodilator
COPD

Answer

sodium channel blocker (Class I antiarrhythmic)
slows rate of depolarisation

Answer

beta blocker
class II antiarrythmic

Answer

potassium channel blocker
class III antiarrythmic
prolongs repolarisation and refractory period

Answer

calcium channel blocker
class IV antiarrythmic
shortens plataeu

Answer

Dopamine antagonist
antiemetic

Answer

purine antagonist
used to treat gout

Answer

adsorption agent (adsorbs water)
Anti-diarrhoea drug

Answer

bulk forming laxative
adds to bulk therefore aids peristalsis

Answer

osmotic laxative

Answer

antimuscarinic used to abolish reflex vagal cardiac slowing/asystole and bradycardia
may lessen degree of partial heart block
stimulates AV node

Answer

slows conduction though the AV node
used to see if tachycardia is supraventricular (will abolish) or ventricular (no effect)

Question 29

29

Decarbazine

Question 30

30

Cyclophosphamide

Question 31

31

Rituximab

Question 32

32

Doxorubicin

Question 33

33

Pacitaxal

Question 34

34

5-flurouracil

Question 35

35

Etoposide

Question 36

36

Vinblastine

Question 37

37

Imatinib

Question 38

38

Tretinoin

Question 39

39

Cisplatin

Question 40

40

what is the suffix of ACE inhibitors

-IPRIL

Question 41

41

Amiloride

Question 42

42

furosemide

Question 43

43

thiazide diuretic

Question 44

44

mannitol

Question 45

45

doxazosin

Question 46

46

Spironolactone

Question 47

47

Acetazolamide

Question 48

48

Phenobarbitol

Question 49

49

Desogestrel
Etonogestrel
Levonorgestrel

Question 50

50

Oxytocin

Question 51

51

Dinoprostone

Question 52

52

Azathioprine

Question 53

53

Diclofenac

NSAID

Question 54

54

Celecoxib

Question 55

55

Sulfasalazine

Question 56

56

Ciclosporin

Question 57

57

Salcatonin

Question 58

58

Raloxifine

Question 59

59

Alendronate

Question 60

60

Isoflurane

Question 61

61

Propofol

Question 62

62

Lamotrigine

Question 63

63

Phenytoin

Question 64

64

Brainscape's Knowledge GenomeTM

Year 2 Pharmacology Flashcards Preview

HYMS Pharmacology > Year 2 Pharmacology > Flashcards

Amoxicillin

beta lactam antibioticbroad spectrum

Methicillin

beta lactam antibioticgram positive

cefuroxime

transpeptidase inhibitorbroad spectrum antibiotic

benzylpenicillin

beta lactamgram positive

oxytetracycline

30s inhibitorbroad spectrum

erythromycin

50s inhibitorbroad spectrum

Gentamycin

30s/50s inhibitoraminoglycosidebroad spectrumoto- and nephro-toxicity

Rifampicin

RNA polymerase inhibitorbroad spectrumTB

Trimethoprim

DHF reductase inhibitorUTI

Suxamethoxazole

PABA analoguleUTI

Vancomycin

peptidoglycan inhibitorinterferes with cell wall productiondrug of last resort

Collistin

Polymixinmembrane detergent

Ciprafloxacin

broad spectrumtopoisomerase II inhibitor

Fusidic Acid

EF-G inhibitorcreams and eye drops

Aciclovir

DNA polymerase inhibitornucleotide analogue competes with endogenous nucloetide

Amantidine

viral ion channle disruptor - this prevents viral uncoating

Amprenavir

protease inhibitor

Phenoxymethylpenicillin

transpeptidase inhibitorgram positive

Zidovudine

nucloside reverse transcriptase inhibitor

Clotrimazole

antifungalprevents production of ergosterol

Fluconazole

antifungalprevents the production of ergosterol

Nystatin

antifungalbinds to ergosterol therefore causes formation of pores

Amphoteraxcin

antifungalbinds to ergosterol therefore causes the formation of pores

Pyrimethamine

Antimalarialinhibits DHF reductaseprevents schizoint division

Quinine

AntimalarialInhibits Haem polymerase; prevents parasite detoxification of bloodalso used to treat Crohn's disease (unclear mechanism)

Artemether

Antimalarialresults in the formation of oxygen free radicals which damage infected red blood cells

Griseofulvin

fungal mitosis inhibitor

Clobetasone

steroid

Decarbazine

alkylating chemotherapy agent

Cyclophosphamide

alkylating chemotherapy agent

Rituximab

B cell CD20 antibodyused to treat blood cancers

Doxorubicin

anthracycline antibioticinhibits topoisomerase IIchemotherapy agent

Pacitaxal

microtubule stabilisation agentprevents mitosisused to treat advanced ovarian and breast cancers

5-flurouracil

competes with endogenous nucleotides for encorporation into DNAprevents DNA replication

Etoposide

inhibits topoisomerase IIchemotherapy agent

Vinblastine

tubulin polymerase inhibitordestabilises the mitotic spindle

Imatinib

tyrosine kinase inhibitorused to treat CML

Tretinoin

vitamin A analogueused to treat skin conditions and promyelocytic leukaemia

Cisplatin

Brainscape's Knowledge Genome^TM

beta lactam antibiotic
broad spectrum

beta lactam antibiotic
gram positive

transpeptidase inhibitor
broad spectrum antibiotic

beta lactam
gram positive

30s inhibitor
broad spectrum

50s inhibitor
broad spectrum

30s/50s inhibitor
aminoglycoside
broad spectrum
oto- and nephro-toxicity

RNA polymerase inhibitor
broad spectrum
TB

DHF reductase inhibitor
UTI

PABA analogule
UTI

peptidoglycan inhibitor
interferes with cell wall production
drug of last resort

Polymixin
membrane detergent

broad spectrum
topoisomerase II inhibitor

EF-G inhibitor
creams and eye drops

DNA polymerase inhibitor
nucleotide analogue competes with endogenous nucloetide

transpeptidase inhibitor
gram positive

antifungal
prevents production of ergosterol

antifungal
prevents the production of ergosterol

antifungal
binds to ergosterol therefore causes formation of pores

antifungal
binds to ergosterol therefore causes the formation of pores

Antimalarial
inhibits DHF reductase
prevents schizoint division

Antimalarial
Inhibits Haem polymerase; prevents parasite detoxification of blood
also used to treat Crohn's disease (unclear mechanism)

Antimalarial
results in the formation of oxygen free radicals which damage infected red blood cells

B cell CD20 antibody
used to treat blood cancers

anthracycline antibiotic
inhibits topoisomerase II
chemotherapy agent

microtubule stabilisation agent
prevents mitosis
used to treat advanced ovarian and breast cancers

competes with endogenous nucleotides for encorporation into DNA
prevents DNA replication

inhibits topoisomerase II
chemotherapy agent

tubulin polymerase inhibitor
destabilises the mitotic spindle

tyrosine kinase inhibitor
used to treat CML

vitamin A analogue
used to treat skin conditions and promyelocytic leukaemia

loop diuretic
inhibits NKCC2

aldosterone antagonist
potassium sparing diuretic

barbituate
GABA agonist

Desogestrel
Etonogestrel
Levonorgestrel

synthetic versions of progesterone
Contraception

used to induce labour
stimulates uterine contraction

Prostaglandin E2
used to induce labour

inhibits purine synthesis
used to treat autoimmune conditions

immunosuppressant
used to treat autoimmune conditions (RA, IBD)

Calcitonin preparation
Osteoporosis

SERM
HRT; osteoporosis

Bisphosphonate
Osteoporosis

sodium channel inhibitor
used to treat epilepsy

sodium channel inhibitor
used to treat epilepsy
not used for absence seizures

sodium channel inhibitor
used to treat epilepsy

inhibits GABA transaminase therefore potentiates the action of GABA
epilepsy