Yersinia and Pseudomonas

Question 1

MC Yersinia species causing human disease

Answer 1

Y. enterocolitica

Question 2

Produces fever and abdominal pain that can mimic appendicitis

Answer 2

Y. enterocolitica

Question 3

MCC of bubonic plague

Answer 3

Y. pestis

Question 4

Major animal reservoir of yersinia

Answer 4

Pigs

Question 5

Patients at risk for yersinia infection

Answer 5

Patients with iron overload (hemochromatosis, thalassemia, sickle cell disease)

Question 6

G- bacteria associated with Kawasaki disease

Answer 6

Yersinia

Question 7

T/F Yersinia enterocolitis in an immunocompetent patient is a self-limiting disease, and no benefit from antibiotic therapy is established

Answer 7

T

Question 8

Recommended emipirical treatment for children with Yersinia infection if warranted

Answer 8

TMP-SMX

Question 9

MC mode of transmission of Y pestis to humans

Answer 9

Bite of infected Xenopsyla cheopsis fleas

Question 10

3 principal clinical presentations of plague

Answer 10

1) Bubonic 2) Septicemic 3) Pneumonic

Question 11

MC clinical presentation of plague

Answer 11

Bubonic

Question 12

Buboes of bubonic plaque refer to

Answer 12

Lymphadenitis

Question 13

MC site of lymphadenitis of yersinia pestis/bubonic plague

Answer 13

Inguinal

Question 14

Black death

Answer 14

Yersinia pestis/Bubonic plague; causes purpura and gangrene of the extremiites as a result of intravascular coagulation

Question 15

Least common but most dangerous and lethal for of yersinia infection

Answer 15

Pneumonic

Question 16

Historical DOC for bubonic plague

Answer 16

Streptomycin

Question 17

Post exposure prophylaxis for close contacts of patients with pneumonic plague

Answer 17

1) Tetracycline 2) Doxycycline 3) TMP-SMX; given within 7 days of exposure

Question 18

T/F P aeurginosa is a strict aerobe

Answer 18

T

Question 19

P aeruginosa: ?lactose ferm ?oxidase ?hemolytic pattern

Answer 19

Non-lactose fermenting, oxidase positive, beta hemolytic

Question 20

Ecthyma gangrenosum

Answer 20

P aeruginosa

Question 21

Pink macules that progress to hemorrhagic nodules and eventually to ulcers with ecchymotic and gangrenous centers with eschar formation, surrounded by intense red areola

Answer 21

Ecthyma gangrenosum

Question 22

Appropriate for single-agent therapy for Pseudomonas infection

Answer 22

Cefta, pip-taz, cefepime, ticarcillin-clavulanate