zer to finals conditions Flashcards

1
Q

what are the causes of MS

A

genes, epstein-barr virus, low vitamin D, smoking and obesiy

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2
Q

other causes of optic neuritis that arent MS

A

sarcoidosis, syphilis, measles, lyme disease

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3
Q

how to treat MS relapses

A

steriods

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4
Q

what do you look for in a lumbar puncture of MS

A

oligoclonal bands in the CSF

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5
Q

what is lhermittes sign

A

electric shock sensation that travels down spine and into limbs when flexing the neck.

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6
Q

what is the most common type of MND

A

amyotrophic lateral sclerosis

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7
Q

what is progressive bulbar palsy

A

Affects the muscles of talking and swallowing

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8
Q

signs of a lower motor neuron disease

A

muscle wasting, reduced tone, fascicilations, reduced reflexes

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9
Q

signs of upper motor neurons

A

increased tone, brisk reflexes and upgoing plantar reflexes

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10
Q

what drugs slows progression of ALS

A

riluzole

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11
Q

side effects of sodium valproate

A

teratogenic, liver damage, hair loss and tremor

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12
Q

how does sodium valproate work

A

increases activity of GABA which is an inhibitory neurotransmitter

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13
Q

drugs to treat generalised tonic- clonic seizure

A

men- sodium valproate
women- lamotrigine or levetiracetam

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14
Q

how do you treat a partial seizure

A

lamotrigine or levetiracetam

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15
Q

how to treat myoclonic seizure

A

men- sodium valproate
women- levetiracetam

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16
Q

how do you treat absent seizures

A

ethosuximide

17
Q

what is status epilepticus

A

seizures lasting more than 5 minutes

18
Q

management of status epilepticus

A

midazolam, diazepam

19
Q

what is myasthenia gravis

A

autoimmune conditin affecting the neuromuscular junction.

20
Q

what symptoms do you experiences with myasthenia gravis

A

muscle weakness that gets worse with activity

21
Q
A
22
Q

what tumour is myastheia gravis associated with

A

thymomas

23
Q

treatment for myasthenia gravis

A

cholinesterase inhibitor
immunosupressors

24
Q

what viruses trigger guillian barre syndrome

A

campylobacter jejuni, epstein barr virus

25
Q

how do you diagnose guillian barr syndrome

A

nerve conduction studies
lumbar puncture looking for raised protein with normal cell and glucose count