김하영 Flashcards
미생물1-2중간 (32 cards)
accelular infecious agent
virus
the smallest
piconavirus
piconaviridae
the largest
poxviridae
range of size
0.02-0.3 micrometers
obligate intracellular parasite 3개
Rickettsia
Chlamydia
Virus
obligate intracellular parasite 특징
no built in metabolic machinery
no ribosome > no enzyme( rickettsia 는 있다)
complex nucleocapsid
bacteriophage
hlical nucleocapsid
ebola, influenza(enveloped), tobacco mosaic
polyhedral nucleocapsid (icosahedral)
mastadenovirus
tails
bacterial viruses, bacteriophages
envelopes
animal viruses
hemagglutination assay
highest dilution clump RBC
plaque assay
on host cell, PFU
infectious dose, lethal dose
smallest amount to kill 50% > ID50
lytic bacteriophages
- attachment
- penetration
- biosynthesis
- maturation ( tail > capsid > tail fiber )
- release
lysogenic multiplication
- attachment
- penetration
- DNA recombination
- lysogenic bacteria reproduce
- prophage DNA recombination 분리
- go to lytic cycle
animal viruses
- attachment, adsorption
- penetration
- uncoating of viral nucleic acids
- biosynthesis
- maturation, assembly of virus capsids
- virus release
animal virus attachment
receptor
animal virus penetration -fusion
HIV, herpes
endocytosis - enveloped
adenovirus, influenza virus
budding release
enveloped - influenza, HIV
chronic virus infection
always detectable
mild, absent for long period
latent virus infection
stops reproducing, remain dormant
not detectable
latent virus 종류
Herpes simplex type 1 - cold scores
Varicella zoster virus - chicke pox, shingles
