arthropod-borne disease

Question 1

arthropod bacteria disease

Answer 1

Lyme Disease
Plague
Rickettsial Diseases
Malaria
Q fever
Tularemia

Question 2

anthropod virus disease

arboviruses

Answer 2

Encephalitis
Yellow fever
Colorado tick fever

Question 3

anthropod two way

Answer 3

Man-Arthropod-Man

Animal-Anthropod-Man

Question 4

anthropod vectors

Answer 4

Aedes Aegyti - 모기임
Culex Mosquito - 애도 모기
Assorted Ticks - 애는 진드기
Phlebotmine Sandfly

Question 5

Lyme Disease

Answer 5

2. anthro bac disease- tick 장상피>침샘
   Borrelia burgdorferi
   B. garinii
   B. afzelii (spirochete)

Question 6

LD 증상

Answer 6

skin lesion, neurological abnormalities,

heart inflammation, arthritis, Alzheimer-like

Question 7

Plague (Select Agent)

Answer 7

2. anthro bac- flea (쥐)
   Yersinia pestis (G-)
   페스트 혹은 흑사병

Question 8

Plague spread

Answer 8

벼룩 > 사람 뭄 > 사람끼리는 공기 > 폐렴> 패혈증
피와 림프에서 증식
식세포 작용에서도 증식

키우는 쥐는 죽는데, 야생쥐는 산다

Question 9

plaque molecular mechanism

Answer 9

plasmids and paathogenicity island

1. Specialized type 3 secretion system
2. Yop(Yersinia outer proteins) : prevent 식세포, adhesion, macrophage death induction

Question 10

tularemia

Answer 10

2. anthro bac disease- rabbit fever: tick, mosquito, fly
Francisella tularensis (G-)

Question 11

Rickettsial Diseases

Answer 11

2. anthro bac disease - flea, lice, ticks
   Rickettsia prowazekii (G-)
   Rickettisa rickettsii

인공배지 x > 조직에 배양
gene 치명적 : vir B (진화과정중 작아져서)
척수동물 세포내에서만 존재(주로 포유류)

Question 12

Rickettsia prowazekii

Rickettsia rickettsii

Answer 12

P : typhus fever > rat

R : Rocky Mountain spotted fever > tick

Question 13

Malaria

Answer 13

2. arthro bac disease- parasite, mosquito
   Plasmodium vivax
   Plasmodium falciparum

1 million/ 100million die

Question 14

sporozites > 간에서 성숙 merozites > 적혈구gametocytes > 흡혈

Answer 14

malaria 이동

Question 15

말라리아 증상

Answer 15

열 오한 두통, 전신 통등, 심계항진, 식욕부진, 수면장애

Question 16

Q fever (Select Agent)

Answer 16

2. anthro bac disease - ticks, dust
Coxiella burnetii (G-, endospore)

farmers
lung- mild respiratory symptom, acute headache, muscle pain, fever
endocarditis (5-10년 후)

Question 17

Arbovirus 설명

Answer 17

by bloodsucking arthro.> vertebrate
anthro에서는 no disease
immunity permanent
no vaccine
-undiffereentiated fever (단기적 열 + 불특정 증상)
-Encephalitis (뇌염) : inflammation of the brain , 사망률 높다
-homorrhagic fevers : 심각하고 치명

Question 18

Equine Encephalitis

Answer 18

2. arbovirus disease - mosquito(aedes, culex) > 쥐, 새, 말
   Togaviridae, Alphavirus

enveloped, plus-strand RNA
death
location - EEE, VEE, WEE

Question 19

EEE
VEE
WEE

Answer 19

EEE- Atlantic, Southern Coast - Aedes - bird - 70%
VEE- Southern United States - Aedes, Culex- 쥐, 말-아이 30%, 어른 10% 이하
WEE- Mountains of West - culex - 새 - 7%

Question 20

togavirus

Answer 20

2.. arbovirus - encephalis
enveloped, plus -strand RNA
알려진거 30종류 이상

Question 21

Flaviviruses

Answer 21

2. arboviridae - Dangue, West nile, Yellow fever
   flaviviridae family
   plus-strand RNA
   cytoplasmic membranes

Question 22

Dengue

Answer 22

2. arbovirus disease - Aedes aegypti, Aedes albopictus
   flavivirus

4개 serotypes
human 50 million/ year
2.5 billion risk
Texas

Question 23

Dengue pathogenesis

Answer 23

1. dengue fever

2. homorrhagic fever

Question 24

West Nile Fever (encephalitis)

Answer 24

2. arbovirus disease- culex, bird(sparrow, crow), 수혈

Uganda
fever, lymphadenopathy(림프샘장애), rash
1% 이하에서 심각한 encephalitis

Question 25

Tick - Borne Encephalitis

Answer 25

2. arbovirus disease: tick, unpasturized dairy products

Question 26

Yellow fever (황열)- bioweapon

Answer 26

2. arbovirus disease : human or monkey>human
   **acute viral hemorrhagic disease
   female mosquito
   fever, chills, headache, backache, nausea, vomit
   심각: jaundice, lesion, homorrhaging 장기

Question 27

Bunyaviruses

Answer 27

2. arbovirus
   bunyaviridae
   enveloped, -ssRNA virus
   5 genera : Nairovirus, Orthobunyavirus, Phlebovirus, Hantavirus, Tospovirus

Question 28

Bunyaviridae Tripartite genomes

Answer 28

three gene segments
S- small : nucleocapsid
M- medium: glycoproteins G1, G2
L- lage : RNA ploymerase

Question 29

Bunyaviruses five genera

Answer 29

nairovirus
orthobunyavirus : la crosse virus - encephalitis
phlebovirus : sandfly fever, homorrhagic fever
hantavirus : rodent- borne
Tospovirus : plant viruses

Question 30

Colorado tick fever virus

Answer 30

2. arbovirus - tick
   Reoviridae, Colorado tick fever virus

haemopoietic cells, erythrocytes
western US, Canada, high mountains