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Flashcards in 01 Introduction Deck (32)
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1

Substance capable of inducing an immune response

Antigen

2

Antigen that is not intrinsically present in the human body

Foreign/Non-self antigen

3

Antigen that is an intrinsic part of the human body

Self Antigen

4

Antigens in nucleated cells that are matched prior to organ transplantation

Human Leukocyte Antigen (HLA)

5

Antigens in anucleated cells that are matched prior to blood transfusion

Blood Group Antigen

6

Capacity of the immune system to differentiate self from non-self, harmless from harmful

Tolerance

7

Exaggerated response of the immune system towards harmless antigens

Hypersensitivity Reaction

8

Antigen that triggers hypersensitivity reaction

Allergen

9

The immune system attacks and destroys self antigens due to its inability to distinguish self from non-self

Autoimmune disease

10

Antibodies that attack self-antigens

Autoantibodies

11

Antinuclear antibodies attack the components of the nucleus of the cells in the body

Systemic Lupus Erythematosus (SLE)

12

Common cause of death of SLE patients

Kidney failure

13

Cancer of the bone marrow results in the release of immature blood cells into circulation

Immunoproliferative disease

14

High cell count, mostly blast cells in the blood

Leukemia

15

High cell count, mostly blast cells in the lymphoid organs

Lymphoma

16

Due to decrease leukocyte count or decreased leukocyte function

Immunodeficiency disorder

17

Field of immunology concerning cells that destroy cancerous cells

Tumor Immunology

18

Antigens expressed by cancer cells in abnormal levels

Tumor markers

19

Tumor marker for pancreatic cancer

CA 19-9

20

Tumor marker for ovarian cancer

CA 15-3

21

Tumor marker for colorectal cancer

Carcinoembryonic antigen (CEA)

22

Matching of HLAs prior to organ transplantation

Transplantation Immunology

23

Method of manipulating the immune system via introduction of attenuated organism into the body

Vaccination / Immunization

24

Ability to cause disease

Pathogenicity

25

Ability to stimulate antibody production

Immunogenicity

26

Study of antigen-antibody reaction

Serology

27

Antibodies react with different but closely related antigen

Cross reactivity

28

Immunoassays, Immunofluorescense, Chemiluminescence

Primary Reactions

29

Agglutination, Precipitation, Flocculation, Complement-fixation

Secondary Reactions

30

In vivo tests

Tertiary Reactions