04.08 - CV Misc 1 (Nichols)

Question 1

Transverse bands of hyper-contracted sarcomeres is called

Answer 1

Contraction banding

Question 2

2 Malignant Vascular Neoplasms

Answer 2

Angiosarcomas, Hemangiopericytoma

Question 3

A large facial telangiectasia in a child w mental deficiency may indicate

Answer 3

Presence of additional vascular malformations

Question 4

Age and race of Prinzmetal angina

Answer 4

Japanese less than 50

Question 5

Arterial ulcers, in contrast to venous, are

Answer 5

painful, punched out or stellate. Surrounding skin red and taut

Question 6

Autosomal dominant disorder caused by mutations in TGF-beta signaling in endothelial cells

Answer 6

Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu)

Question 7

Benign, very painful tumors arising from specialized SM cells of Glomus Bodies

Answer 7

Glomus Tumors

Question 8

Capillary hemangiomas that manifest as rapidly growing red pedunculated lesions on skin, gingival, or oral mucosa

Answer 8

Pyogenic Granulomas

Question 9

Cavernous Hemangiomas are one component of

Answer 9

von Hippel-Lindau Disease

Question 10

CD31 is a marker for

Answer 10

Endothelial cells

Question 11

Compared with Capillary Hemangiomas, Cavernous Hemangiomas are

Answer 11

More infiltrative, deeper, do not spontaneously regress

Question 12

Coronary artery hyperreactivity is sometimes called

Answer 12

Cardiac Raynaud

Question 13

Endothelial cell marker

Answer 13

CD31

Question 14

Erythematous, scaling, and eczematous patches or plaques on LE’s

Answer 14

Stasis Dermatitis frequently presents with

Question 15

Good test for DVT

Answer 15

D-Dimer

Question 16

Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu) is caused by mutations in

Answer 16

TGF-beta signaling in endothelial cells

Question 17

Hereditary Hemorrhagic Telangiectasia is aka

Answer 17

Osler-Weber-Rendu

Question 18

Histologic Findings in acute cases of Ischemic Dilated CM (Takotsubo CM)

Answer 18

Contraction band necrosis

Question 19

Homans Sign

Answer 19

Calf pain with forceful dorsiflexion of foot (not a good test)

Question 20

How do the bac’s in Bacillary Angiomatosis cause proliferation

Answer 20

Induce host tissues to produce HIF-1alpha, which drives VEGF

Question 21

How long does Prinzmetal angina last

Answer 21

5-15 minutes

Question 22

How often do emboli occur from varicose veins

Answer 22

Rarely

Question 23

Internal Hemangiomas are commonly found

Answer 23

in liver

Question 24

Major difference between Benign and Malignant Vascular Tumors

Answer 24

Benign form more well-organized vessels

Question 25

Migratory Thrombophlebitis - Trousseau Syndrome

Answer 25

When venous thrombi result from elaboration of procoagulant factors from malignant tumors and thrombos is diff vascular beds

Question 26

Most common vascular ectasia

Answer 26

Nevus Flammeus

Question 27

Most disabling sequelae of Varicose Veins

Answer 27

Edema, Stasis Dermatitis, Ulcerations

Question 28

Most frequently involved location in Venous Stasis Dermatitis

Answer 28

Medial Ankle

Question 29

Most important risk factor for DVT

Answer 29

Prolonged Immobilization (Venous Stasis)

Question 30

Myocardial contraction band necrosis can be due to

Answer 30

Coronary Artery Vasospasm

Question 31

Origin of Angiosarcomas

Answer 31

Endothelial Cells

Question 32

Port Wine Stain lesions occuring in distribution of Trigeminal are associated with

Answer 32

Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis)

Question 33

Prinzmetal Angina is associated with what EKG finding

Answer 33

ST Elevation

Question 34

Spider Telangiectasiasa are most frequently associated with

Answer 34

Hyperestrogenic States

Question 35

Spindle-shaped cells and blood with a light sprinkling of lymphocytes

Answer 35

Kaposi Sarcoma

Question 36

Stasis Dermatitis frequently presents with

Answer 36

Erythematous, scaling, and eczematous patches or plaques on LE's

Question 37

SVC Syndrome is caused by

Answer 37

Neoplasms that compress or invade SVC

Question 38

Syndrome of Myocardial Ischemia, MI, or SCD due to emotional stress

Answer 38

Takotsubo CM

Question 39

Takotsubo CM

Answer 39

Syndrome of Myocardial Ischemia, MI, or SCD due to emotional stress

Question 40

Telangiectasia is used to describe

Answer 40

Permanent Dilation of pre-existing small vessels that form a discrete red lesion

Question 41

Top 3 associations for DVT

Answer 41

Cancer, Hospitalization, Surgery

Question 42

Venous Stasis Ulcers are usually located on

Answer 42

Medial Ankle

Question 43

What accounts for more than 90% of thrombophlebitis and phlebothrombosis

Answer 43

DVT

Question 44

What drives proliferation of Kaposi Sarcoma

Answer 44

Viral homolog of CycD

Question 45

What is Bacillary Angiomatosis

Answer 45

Vascular proliferation in immunocompromised hosts caused by gram-negative bacilli of Bartonella family

Question 46

What leads to Chylous Ascites, Chylothorax, and Chylopericardium

Answer 46

Rupture of dilated lymphatics, typically following obstruction by an infiltrating tumor mass

Question 47

What type of DVT are associated with clinically significant PE

Answer 47

Proximal (above popliteal)

Question 48

When do you see contraction banding

Answer 48

Reperfusion of dead myocardium

Question 49

When venous thrombi result from elaboration of procoagulant factors from malignant tumors and thrombos is diff vascular beds

Answer 49

Migratory Thrombophlebitis - Trousseau Syndrome

Question 50

When will Acute MI take form of contraction band necrosis

Answer 50

Coronary Vasospasm; MI with Reperfusion