04.16 - HTN, Related HD (Nichols) Flashcards

(45 cards)

1
Q

4 Major Types of Hypertrophic Heart Diseases

A

HTN Heart Disease, Hypertrophic Cardiomyopathy, Aortic Stenosis, Cor Pulmonale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

3 Characteristics of HTN HD

A

Diastolic Dysfunction, Impaired Compliance and Ventricular Filling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

4 major types of Hypertrophic Heart Diseases in order or prevalence

A

HTN Heart Disease, Hypertrophic Cardiomyopathy, Aortic Stenosis, Cor Pulmonale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Acute-on-Chronic Cor Pulmonale =

A

RV Dilatation + Hypertrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Age of presentation with Calcifications in Sinuses of Valsalva

A

Over 70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Age range for Bicuspid Aortic Stenosis

A

young and middle-aged adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Age range for Degenerative Calcific Aortic Stenosis

A

> 70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Age range for Rheumatic Aortic Stenosis

A

young and middle-aged adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chronic Cor Pulmonale is characterized by

A

RV (and often R atrial) Hypertrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Criteria for Dx of HTN HD

A

LV Hypertrophy in absence of other CV pathology; Hx or pathologic evidence of HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diastolic Dysfunction, Impaired compliance and Ventricular Filling are characteristic of

A

HTN HD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dilation in HTN HD

A

Usually doesn’t occur until late in process

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Do the same tx’s for atherosclerosis prevention work for calcific aortic stenosis

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Fibrosis is a feature of

A

HCM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fibrosis of HCM can provide the anatomical substrate for

A

Reentrant Ventricular Tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does rheumatic vavlulitis stenose the semilunar valve

A

Inflammation and fibrosis start at the commissure and moves inward

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Hypertrophic CM is associated with asymmetric __

A

hypertrophy of septum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

If aortic valve stenosis is due to previous rheumatic valvulitis, 95% of cases have simultaneous

A

mitral stenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

In Acute Cor Pulmonale, the RV usually shows only

20
Q

In some cases of what are myocytes oriented in abnormal directions (not parallel)

21
Q

Microscopic findings in HTN HD

A

Transverse diameter of myocytes is increased; Boxcar nuclei

22
Q

Myocyte disarray is seen in many cases of

A

Hypertrophic CM

23
Q

Normal LV thickness

24
Q

Normal Ventricular wall thickness

25
Patient with Bicuspid stenosis probably present with
Sudden death
26
Possible Tx for HCOM
Surgical resection; Inject ethanol
27
Presentation of Calcifications in Sinuses of Valsalva
Dyspnea, Angina, or Sudden Death
28
Prevalence of HTN Heart Disease in HTN pts
60% of blacks, 30% of whites
29
Risk factors for Calcific Aortic Stenosis
Nearly same as atherosclerosis
30
RV in Chronic vs Acute Cor Pulmonale
Hypertrophy in Chronic, Dilatation in Acute
31
The myocardial fibrosis in HTN HD and other hypertrophic HD's tends to be
Interstitial
32
Transverse diameter of myocytes is increased; Boxcar nuclei
Microscopic findings in HTN HD
33
Typical symptoms of compensated HTN HD
Usually asymptomatic
34
What causes obstruction of outflow in HCM
Asymmetrically hypertrophied upper septum bulging into outflow tract = HCOM
35
What drives Progressive Myocardial Fibrosis
Cytokines, TGF-Beta
36
What has stenosed the aorta in degenerative calcific aortic stenosis?
Formation of rocks in sinuses of valsalva
37
What is highlighted by trichome stain
Interstitial fibrosis in HCM
38
What proportion of Hypertrophic CM patients have HCOM
One Third
39
Which hypertrophic HD is a surgical emergency
Aortic Stenosis
40
Which hypertrophic HD occurs in RV
Chronic Cor Pulmonale
41
Which hypertrophic HD occurs in young
Hypertrophic CM
42
Which hypertrophic HD's have murmurs
Aortic Stenosis, Hypertrophic CM sometimes
43
Which hypertrophic heart dieases is more prevalent in blacks
HTN HD
44
Which hypertrophic heart disease can be acute
Cor Pulmonale
45
Which hypertrophic heart disease doesn't present with angina
Cor Pulmonale