06-Superficial Fungi I Flashcards

1
Q
  1. Above what level of the hair shaft do dermatophytes infect?
A
  1. Adamson’s fringe
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2
Q
  1. Do candida infections occur in high or low pH? What factors affect the pH conducive to candiasis?
A
  1. High pH; panty-liners, diapers, occlusive agents
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3
Q
  1. What is the most reliable test to distinguish T. rubrum from T. mentag?
A
  1. Hair perforation test
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4
Q
  1. Which dermatophyte is most commonly responsible for tinea gladiatorum?
A
  1. T. tonsurans
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5
Q
  1. What is the causative non-dermatophyte in resistant T. Pedis?
A
  1. Scytalidium dimidiatum – resistant to most antifungals but sensitive to cycloheximide
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6
Q
  1. What organism most commonly causes favus?
A
  1. T.schoenleilli
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7
Q
  1. Define mycelium.
A
  1. A mass of hyphae
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8
Q
  1. What are chlamydoconidia? What organism produces chlamydoconidia?
A
  1. Thick-walled round cells resistant to the environment. T. tonsurans
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9
Q
  1. What is the most common cause of white superficial onychomycosis?
A
  1. T. mentographytes
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10
Q
  1. What accounts for the depigmentation seen in tinea versicolor?
A
  1. Dicarboxylic acid
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11
Q
  1. What is the organism responsible for tinea nigra?
A
  1. Horteae/ Exophiala wernickii
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12
Q
  1. What causes black piedra? What is the clinical presentation?
A
  1. Piedra hortae; brown/black firmly adherent nodules on hair
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13
Q
  1. Malassezia has been implicated in what neonatal skin condition?
A
  1. Neonatal cephalic pustulosis
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14
Q
  1. Name 4 geophilic organisms. What kind of inflammatory response do they elicit in humans?
A
  1. M. gypseum (tinea corporis, capitis), T. terrestre, M. fulvum, M. cookie; modsevere inflammation
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15
Q
  1. Name zoophilic organisms. What kind of inflammatory response do they elicit in humans?
A
  1. M. canis, T. Mentagrophytes, M. gallinae, T. equinum, T. verrucosum, M. nanum, T. simii, M. persicolor; intense inflammation
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16
Q
  1. What are the nutritional requirements for T. verrucosum?
A
  1. Inositol and thiamine.
17
Q
  1. Which dermatophyte requires niacin for its growth?
A
  1. T. equinum
18
Q
  1. How are arthroconidia formed?
A
  1. By fragmentation of hyphae
19
Q
  1. What are sporangia?
A
  1. Spores that are produced in a sac
20
Q
  1. What are conidia?
A
  1. Asexual, nonmotile spores, reproductive structures
21
Q
  1. In which two groups of dermatophytes are macroconidia important?
A
  1. Microsporum and Epidermophyton
22
Q
  1. Name endothrix organisms.
A
  1. T. tonsurans, T. rubrum, T. violaceum. T. soudanense, T. gourvilli, T. yaoudei, T. schoenleinii “say say violet you’re going right to town)
23
Q
  1. Name ectothrix organisms.
A
  1. M. canis, M. audouini, M. distortum, M. ferrugineum, M. gypseum, M. distortum, T. rubrum (sometimes)
24
Q
  1. What causes tinea imbricata?
A
  1. T. concentricum
25
Q
  1. What causes bullous tinea?
A
  1. T. mentographytes
26
Q
  1. What is the most common cause of white superficial onychomycosis in the HIV population?
A
  1. T. rubrum
27
Q
  1. What time period does congenital candidiasis clinically present?
A
  1. Usually at birth, but can be up to 6 days of life
28
Q
  1. What is the clinical distribution of neonatal candidiasis?
A
  1. Diaper area and oral mucosa
29
Q
  1. What does AEPCED stand for and what is the gene mutation?
A
  1. Autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy syndrome, APECED- autosomal recessive AIRE gene
30
Q
  1. What is the gold standard treatment for systemic candidiasis?
A
  1. Amphotericin B
31
Q
  1. What is Jacquet’s erosive dermatitis?
A
  1. An erosive variant of granuloma gluteale infantum (pseudoverrucous papules/nodules in chronic irritant dermatitis)
32
Q
  1. What is geotrichosis and where is it normally found?
A
  1. Yeast-like fungus; normal flora in milk, fruit tomatoes and soil