07 - Neuropharmacology

Question 1

chlorpromazine

Answer 1

typical antipsychotic

Question 2

clozapine

Answer 2

atypical antipsychotic

Question 3

bromocriptine

Answer 3

D2 agonist

Question 4

ropinirole

Answer 4

D2 agonist

Question 5

apomorphine

Answer 5

D2 agonist

rescue treatment for off effects

Question 6

L-DOPA

Answer 6

DA precursor

Question 7

carbidopa

Answer 7

peripheral DDC inhibitor

Question 8

benserazide

Answer 8

peripheral DDC inhibitor

Question 9

salegiline

Answer 9

MAO-B inhibitor

giline

Question 10

rasagiline

Answer 10

MAO-B inhibitor

giline

Question 11

tolcapone

Answer 11

COMT inhibitor

capone

Question 12

entacapone

Answer 12

COMT inhibitor

capone

Question 13

amantadine

Answer 13

Stimulants of DA release

Question 14

benzatropine

Answer 14

anti-muscarinic

tropine

Question 15

moclobemide

Answer 15

MAO inhibitor
reversible inhibitor for MAO-A,
which metabolizes NE, E and 5-HT

Question 16

amitriptyline

Answer 16

TCA

non-selective inhibitors of NET and SERT

Question 17

imipramine

Answer 17

TCA

non-selective inhibitors of NET and SERT

Question 18

fluoxetine (Prozac)

Answer 18

SSRI
(xetine)
selective inhibitor of SERT

Question 19

citalopram

Answer 19

SSRI

selective inhibitor of SERT

Question 20

paroxetine

Answer 20

SSRI
(xetine)
selective inhibitor of SERT

Question 21

sertraline

Answer 21

SSRI

selective inhibitor of SERT (sert)

Question 22

bupropion

Answer 22

NRI

selective inhibitor of NET

Question 23

venlafaxine

Answer 23

SNRI

inhibitors of SERT and NEI

Question 24

mianserin

Answer 24

atypical anti-depressants
monoamine receptor antagonists
alpha(2) heteroreceptor blocker

Question 25

trazodone

Answer 25

atypical anti-depressants | post-synaptic 5-HT(2A) blocker

Question 26

diazepam

Answer 26

``` BDZ potentiates GABA(A) receptor on GABAergic neurone ```

Question 27

lorazepam

Answer 27

``` BDZ potentiates GABA(A) receptor on GABAergic neurone ```

Question 28

midalozam

Answer 28

``` BDZ potentiates GABA(A) receptor on GABAergic neurone ```

Question 29

flumazenil

Answer 29

BDZ antagonist

Question 30

zolpidem

Answer 30

Z drug

Question 31

phenobarbital

Answer 31

enhances GABA(A) receptors

Question 32

vigabatrin

Answer 32

inhibits GABA transaminase

Question 33

valproate

Answer 33

1) inhibits GABA transaminase | 2) inhibits VG Na+ channels

Question 34

carbamazepine

Answer 34

inhibits VG Na+ channels

Question 35

phenytoin

Answer 35

inhibits VG Na+ channels

Question 36

ethosuximide

Answer 36

inhibits T-type Ca2+ channels

Question 37

gabapentin

Answer 37

novel anti-epileptic

Question 38

pregabalin

Answer 38

novel anti-epileptic

Question 39

lamotrigine

Answer 39

1) inhibits VG Na+ channels 2) inhibits T-type Ca2+ channels 3) inhibits glutamate release

Question 40

opioids

Answer 40

activates mule receptors on GABAergic neurone

Question 41

THC

Answer 41

``` cannibinoids activates CB1 (cannabinoid 1) receptor on GABAergic neurone terminal ```