09 Asthma Gallegos Flashcards Preview

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Flashcards in 09 Asthma Gallegos Deck (18):
1

What happens with airway remodeling in asthma?

Inflammation. Mucus hypersecretion. Subepithelial fibrosis. Airway smooth muscle hypertrophy. Angiogenesis. Remodeling usually only happens in chronic uncontrolled asthma

2

What is Atopy?

A risk factor of asthma. The propensity to produce abnormal amounts of IgE in response to exposure to environmental allergens

3

What foods should be avoided with Sulfite Sensitivity?

Processed foods, shrimp, beer, or wine if they cause symptoms

4

What are the key measures of Spirometry?

FVC (forced vital capacity). FEV1 (forced expiratory volume in 1 second)

5

What FEV1 is considered mild, moderate, or severe?

Mild: 61-80. Moderate: 41-60. Severe < 40

6

For treatment step-up, what is preferred in Step 1?

SABA PRN

7

For treatment step-up, what is preferred in Step 2?

Low-dose ICS

8

For treatment step-up, what is preferred in Step 3?

Low-dose ICS + LABA. OR. Medium-dose ICS

9

For treatment step-up, what is preferred in Step 4?

Medium-dose ICS + LABA

10

For treatment step-up, what is preferred in Step 5?

High-dose ICS + LABA and consider Omalizumab for patients who have allergies

11

For treatment step-up, what is preferred in Step 6?

High-dose ICS + LABA + oral corticosteroid and consider Omalizumab for patients who have allergies

12

What are the ICS options?

Beclomethasone, Ciclesonide, Flunisolide, Fluticasone, Budesonide, Mometasone

13

What is the Mast Cell Stabilizer that can be used?

Cromolyn

14

What are the LTRA options?

Montelukast, Zafirlukast, Zileuton

15

What is the Methylxanthine option?

Theophylline

16

What is the "Rules of 2"?

If any of the following are identified, patient may need an adjustment in asthma controller medication (assuming patient is compliant): Daytime symptoms frequency >2/week, Nighttime symptom frequency > 2/month, >2 canisters of SABA/year, 2+ exacerbations/year (/6 months for 0-4 years old). Answering yes to any of these questions may indicate that asthma is not well controlled

17

What is PEK flow based on?

Gender, age, and height

18

What are the LABAs that can be used?

Salmeterol, Formoterol