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Flashcards in 14 Study Guide Deck (114):
1

Which compounds have dipole dipole reactions?

Alcohol, Ketone, etc.

2

Which compounds have dipole dipole reactions?

Alcohol, Ketone, etc.

3

What are some common infusion related ADRs of IVIG?

HA and Arthralgia as well as possible renal toxicity

4

What would be a better choice between Morphine CR and Hydromorphone in a patient that requires acute pain control?

Hydromorphone b/c it has quicker onset relative to controlled release

5

Iron has the best absorption with?

Ascorbic acid

6

What do you take for iron toxicity?

Deferoxamine

7

What is the DDI with Sulfa and Omeprazole?

No DDI with these two agents

8

What are the targeted Phenytoin Levels?

10-20mcg/L

9

What factors are derived from plasma?

Plasma, IVIG, Alpha-something ase, Factor IX

10

Which benzos have no CYP metabolism?

LOT: Lorazepam, Oxazepam, Temazepam. Glucuronidation only, good for elderly

11

Which statins have the most CYP?

SAL: Simvastatin, Atorvastatin, Lovastatin

12

Which statins have the fewest CYP interaction?

Pravastatin, Rosuvastatin, Fluvastatin

13

Which analgesic requires CYP for activation?

Codeine (2D6 to morphine)

14

Where would you look up a generic name that your pharmacy doesn't have?

Red Book

15

Which drug indicates that a patient needs pneumococcal vaccine?

Digoxin

16

What medication for constipation is most low acting?

Psyllium

17

What do you give for gout attack?

NSAID first line

18

What is a serious ADR of Xolair?

Anaphylaxis

19

What should be remembered about Medrol dose pack?

Take with food and may cause insomnia

20

What are some short acting steroids?

Hydrocortisone/Cortisone

21

What are some intermediate acting steroids?

Methylprednisone, Prenisolone, Prednisone

22

What are some long acting steroids?

Beta/dexamethasone

23

What is the correct dose for prednisone for acute asthma exacerbation?

40mg daily for 6 days

24

What is a DM medication that is used to decrease post-prandial glucose?

Sulfonylureas, Meglitinides

25

What can an alcoholic take that could potentially protect her liver?

Milk thistle

26

When is a patient with COPD a candidate for empiric Abx treatment?

Increased sputum purulence, Increased sputum volume, Dyspnea

27

What is TACE as it relates to TNF and IL-1?

Binding to soluble TNF

28

An 8 year old boy is prescribed prednisone 20mg PO QD #100. What would you counsel his parent about?

Don't d/c w/o consulting MD first. This medication can cause growth suppression

29

Which BBs are approved for CHF?

Coreg and Metoprolol Succinate

30

What is normal Prothrombin Time?

10-13 seconds

31

What is the time window to use antiplatelet drugs for stroke?

3 hours (up to 4.5h for certain circumstances)

32

What are the different LDL goals, considering CVD?

< 100 if no over CVD. < 70 if overt CVD

33

If you're trying to target TGs for a patient before anything else, what are the best agents to use?

Fibrates! Niacin is a second line agent

34

What factors can decrease INR?

St. Johns Wort. CoQ10. Ginseng. Green tea

35

What factors can increase INR?

Fish oil. Garlic. Ginger. Gingko. Vitamin E

36

What are the GPIIb/IIIa inhibitors?

TEA: Tirofiban. Eptifibitide. Abciximab

37

Patient needs a diuretic but has had SJS in the past, what would you give?

Ethacrynic acid

38

When are ACE-I/ARBs CI?

3rd trimester pregnancy

39

Patient needs HTN med that increases K level?

Spironolactone

40

CCB that decreases HR?

Verapamil and Diltiazem

41

What are the effects of Hypothyroidism on coumadin?

Hypothyroidism will cause a delayed response to coumadin d/t the slow metabolism of clotting factors by the liver

42

Zometa (Zolindronic acid) for osteoporosis, whats the dose?

5mg IV Q yearly

43

How would you know if patient has Folic Acid deficiency anemia?

High MCV. B12 is normal

44

Which DM medications have BBWs?

Metformin (lactic acidosis). Pioglitazone (cause or exacebate CHF)

45

What what A1c do you initiate dual therapy?

7.5-9

46

Physician orders a 10U IV bolus, what type of insulin do you give?

Only R insulin can be given as bolus

47

Which insulin is most like endogenous insulin?

Glargine or Lantus

48

What are the birth control pills starting/back up requirements?

Sunday start: back up for 7 days. Start on first day of bleeding, no backup necessary

49

What is used for HPA axis suppression?

Prednisone daily for long term

50

What can be used OTC for menopause?

Black cohosh

51

A patient has adrenal insufficiency d/t a tumor, what should be given?

Testosterone. Aldosterone

52

What is best to decrease postprandial glucose level?

Forgot to type it in... Whoops

53

Antibiotic coverage for atypical microbes?

Doxycycline and Clarithromycin

54

Patient with foot debridement, Abx?

Cefotetan

55

Other than Strep pneumo, what organism causes CAP in otherwise healthy individuals?

Mycoplasma

56

What drugs cause urine discoloration?

Phynazopyridine. Nitrofurantoin. Rifampin

57

Which drug for overactive bladder is available in a patch?

Oxybutynin

58

Elderly needs antihistamine for sleep, what would you give?

Loratidine

59

What are some common infusion related ADRs of IVIG?

HA and Arthralgia as well as possible renal toxicity

60

What would be a better choice between Morphine CR and Hydromorphone in a patient that requires acute pain control?

Hydromorphone b/c it has quicker onset relative to controlled release

61

Iron has the best absorption with?

Ascorbic acid

62

What do you take for iron toxicity?

Deferoxamine

63

What is the DDI with Sulfa and Omeprazole?

No DDI with these two agents

64

What are the targeted Phenytoin Levels?

10-20mcg/L

65

What factors are derived from plasma?

Plasma, IVIG, Alpha-something ase, Factor IX

66

Which benzos have no CYP metabolism?

LOT: Lorazepam, Oxazepam, Temazepam. Glucuronidation only, good for elderly

67

Which statins have the most CYP?

SAL: Simvastatin, Atorvastatin, Lovastatin

68

Which statins have the fewest CYP interaction?

Pravastatin, Rosuvastatin, Fluvastatin

69

Which analgesic requires CYP for activation?

Codeine (2D6 to morphine)

70

Where would you look up a generic name that your pharmacy doesn't have?

Red Book

71

Which drug indicates that a patient needs pneumococcal vaccine?

Digoxin

72

What medication for constipation is most low acting?

Psyllium

73

What do you give for gout attack?

NSAID first line

74

What is a serious ADR of Xolair?

Anaphylaxis

75

What should be remembered about Medrol dose pack?

Take with food and may cause insomnia

76

What are some short acting steroids?

Hydrocortisone/Cortisone

77

What are some intermediate acting steroids?

Methylprednisone, Prenisolone, Prednisone

78

What are some long acting steroids?

Beta/dexamethasone

79

What is the correct dose for prednisone for acute asthma exacerbation?

40mg daily for 6 days

80

What is a DM medication that is used to decrease post-prandial glucose?

Sulfonylureas, Meglitinides

81

What can an alcoholic take that could potentially protect her liver?

Milk thistle

82

When is a patient with COPD a candidate for empiric Abx treatment?

Increased sputum purulence, Increased sputum volume, Dyspnea

83

What is TACE as it relates to TNF and IL-1?

Binding to soluble TNF

84

An 8 year old boy is prescribed prednisone 20mg PO QD #100. What would you counsel his parent about?

Don't d/c w/o consulting MD first. This medication can cause growth suppression

85

Which BBs are approved for CHF?

Coreg and Metoprolol Succinate

86

What is normal Prothrombin Time?

10-13 seconds

87

What is the time window to use antiplatelet drugs for stroke?

3 hours (up to 4.5h for certain circumstances)

88

What are the different LDL goals, considering CVD?

< 100 if no over CVD. < 70 if overt CVD

89

If you're trying to target TGs for a patient before anything else, what are the best agents to use?

Fibrates! Niacin is a second line agent

90

What factors can decrease INR?

St. Johns Wort. CoQ10. Ginseng. Green tea

91

What factors can increase INR?

Fish oil. Garlic. Ginger. Gingko. Vitamin E

92

What are the GPIIb/IIIa inhibitors?

TEA: Tirofiban. Eptifibitide. Abciximab

93

Patient needs a diuretic but has had SJS in the past, what would you give?

Ethacrynic acid

94

When are ACE-I/ARBs CI?

3rd trimester pregnancy

95

Patient needs HTN med that increases K level?

Spironolactone

96

CCB that decreases HR?

Verapamil and Diltiazem

97

What are the effects of Hypothyroidism on coumadin?

Hypothyroidism will cause a delayed response to coumadin d/t the slow metabolism of clotting factors by the liver

98

Zometa (Zolindronic acid) for osteoporosis, whats the dose?

5mg IV Q yearly

99

How would you know if patient has Folic Acid deficiency anemia?

High MCV. B12 is normal

100

Which DM medications have BBWs?

Metformin (lactic acidosis). Pioglitazone (cause or exacebate CHF)

101

What what A1c do you initiate dual therapy?

7.5-9

102

Physician orders a 10U IV bolus, what type of insulin do you give?

Only R insulin can be given as bolus

103

Which insulin is most like endogenous insulin?

Glargine or Lantus

104

What are the birth control pills starting/back up requirements?

Sunday start: back up for 7 days. Start on first day of bleeding, no backup necessary

105

What is used for HPA axis suppression?

Prednisone daily for long term

106

What can be used OTC for menopause?

Black cohosh

107

A patient has adrenal insufficiency d/t a tumor, what should be given?

Testosterone. Aldosterone

108

What is best to decrease postprandial glucose level?

Forgot to type it in... Whoops

109

Antibiotic coverage for atypical microbes?

Doxycycline and Clarithromycin

110

Patient with foot debridement, Abx?

Cefotetan

111

Other than Strep pneumo, what organism causes CAP in otherwise healthy individuals?

Mycoplasma

112

What drugs cause urine discoloration?

Phynazopyridine. Nitrofurantoin. Rifampin

113

Which drug for overactive bladder is available in a patch?

Oxybutynin

114

Elderly needs antihistamine for sleep, what would you give?

Loratidine