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Question 1

___________ new growth composed of cells, originally derived from normal tissues, that have undergone heritable genetic changes allowing them to become relatively unresponsive to normal growth control and to expand beyond their normal anatomic boundaries.

Answer 1

Neoplasm

Question 2

Other common term

Answer 2

1. Tumor = swelling
2. Cancer = crab

Question 3

Tumor , neoplasm refers to
Cancer

Answer 3

Benign and malignant growth
Malignant growth

Question 4

________ study of neoplasia

Answer 4

Oncology

Question 5

Benign tumor

Answer 5

Don’t invade surrounding tissue, and don’t spread to new anatomic location within body, these Tumor can treated and rarely response to kill host

Question 6

Malignant tumor

Answer 6

Invade locally ,spread by metastasis, untreated and will kill the host

Question 7

Tumor in nervous system

Answer 7

very rarely metastasize, but many of these tumors are notably invasive and kill their hosts, thus these tumors are malignant.

Question 8

Tumor occur a stepwise , preneoplastic :

Answer 8

1. Hyperplasia
2. Metaplasia
3. Dysplasia

Question 9

___________: Transformation of one differentiated cell type into another.

Answer 9

Metaplasia

Question 10

__________ Increased cell number in a tissue.

Answer 10

Hyperplasia

Question 11

__________: Abnormal pattern of tissue growth.

Answer 11

Dysplasia

Question 12

Nomenclature:
- Most tumors appears to consist of a single cell type, and name of neoplasm reflects cell type ( ________ or __________ ) from which the tumor is presumed to arise.

Answer 12

mesenchymal, epithelium

Question 13

_______ arise in cells of embryonic mesodermal origin.

Answer 13

Tumor mesenchymal

Question 14

Mesenchymal:
- Benign tumors originating form mesenchymal cells are usually named by adding the suffix - _____ to name of cell of origin.

Answer 14

oma

Question 15

________: benign tumor derived from a lipocyte (fat cells).
________: benign tumor of fibroblast origin.

Answer 15

Lipoma
Fibroma

Question 16

mesenchymal:
- Malignant tumor of mesenchymal origin is ________, a prefix or modifier indicates the tissue of origin.

Answer 16

sarcoma

Question 17

______________: A malignant tumor of lipocyte origin.
______________: A tumor composed of malignant fibroblasts.

Answer 17

Liposarcoma
Fibrosarcoma

Question 18

The cells comprising the hematopoietic system are

Answer 18

Mesenchymal

Question 19

Tumors arising from circulating blood cells or their precursors are termed

Answer 19

Leukemias

Question 20

Neoplastic hematopoietic cells are usually found in large numbers in blood stream, although they may also form

Answer 20

Solid tumor mass

Question 21

Epithelial Tumors
- All of the three embryonic cell layers - ________, _______, and _______ – can give rise to epithelial tissue and to tumors from this tissue.

Answer 21

Endoderm, ectoderm, mesoderm

Question 22

Epithelial Tumors
Benign tumors that arise from glandular epithelium are called ________.

Answer 22

Adenoma

Question 23

The term _________ refers to benign exophytic growth arising from an epithelial surface (proliferating externally or on the surface epithelium).

Answer 23

papilloma

Question 24

_______: A grossly visible, benign epithelial tumor projecting from a mucosal surface.

Answer 24

Polyp

Question 25

All malignant tumors of epithelial origin are termed_______

Answer 25

Carcinoma

Question 26

Carcinoma and adenocarcinomas that stimulate the formation of abundant collagen in surrounding connective tissue may be termed

Answer 26

Scirrhous

Question 27

The neoplastic epithelial cells of mucinous carcinoma and adenocarcinoma produce abundant _______.

Answer 27

mucin

Question 28

_________ is a preinvasive form of carcinoma that remians within the epithelial structure from which it arises and does not penetrate the basement membrane to enter stroma.

Answer 28

Carcinoma in situ

Question 29

Mixed tumors are believed to arise from a single __________ or ___________ cell capable of differentiating into a variety of more mature cell types.

Answer 29

Pluripotential, totipotential

Question 30

The appearance of some malignant tumors gives no clue to their cell of origin, thus they are termed

Answer 30

Undifferentiated neoplasm

Question 31

Teratomas and teratocarcinomas arise from totipotential germ cells thus they contain tissue derived from all embryonic cell layers and consist of a bizarre mixture of adult and embryonic tissue types.

Answer 31

Teratomas, Teratocarcinoma

Question 32

Example: mixed mammary gland tumor composed of a variable admixture of neoplastic,

Answer 32

Epithelial elements: luminal epithelium, myoepithelium. Mesenchymal element: cartilage, bone, fibrous connective tissue, fat.

Question 33

Tumor-like lesions ___________: Disorganized but mature mesenchymal or epithelial tissues found in their normal anatomic location. Many of hamartomas identified in animals consist of abnormal proliferations of blood vessels.

Answer 33

Hamartomas

Question 34

Tumor-like lesions: _________: Are composed of normal mature tissue located at an ectopic site. Example is ________ (mass consisting of mature skin and its appendages which may be found in a variety of unusual sites, including the cornea.

Answer 34

Choristomas: dermoid

Question 35

A significant difference between veterinary and human nomenclature is that a benign tumor arising from melanocytes is - termed a “__________” or “_________” by veterinary pathologists and a “nevus” by medical pathologists. - Medical pathologists reserve the term ______ for a malignant tumor of melanocyte origin, whereas veterinary pathologists term such tumors “___________”.

Answer 35

- benign melanoma, melanocytoma, nevus - melanoma, malignant melanomas