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1-50 Flashcards

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1
Q

Pharmacodynamics is

A

The part of pharmacology, which
deals with what a drug does to the
body

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2
Q

Which of the following types of drugs binds
to a receptor and produce an effect similar to
that of endogenous ligands?

A

Agonist

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3
Q

Drugs ‘x’ binds to drug ‘y’ as a result of which an inactive complex is formed. This
type of antagonism is called

A

Neutralizing antagonism

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4
Q

Epinephrine and acetylcholine act on the sympathatetic and parasympathetic autonomic nervous system, respsectively, and their effects are opposite to each other. This type of antagonism is called

A

Physiologic antagonism

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5
Q

Which of the following is not true about
competitive antagonism?

A

It is reversible

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6
Q

The relative measure f the safety and effectiveness of a drug is the ratio of TD50 to ED50. The pharmacological term used to
indicate this ratio is known as

A

Therapeutic index

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7
Q

A physician may prescribed carbidopa along with levodopa to increase the halflife levodopa and the duration of its antiparkinsonian effect. This way of enhancing of drug effect is known as

A

Potentiation

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8
Q

Which of the following is the main organ of
metabolism?

A

Liver

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9
Q

Chloramphenicol is known for which of the
following adverse side-effects?

A

Gray baby syndrome

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10
Q

Co-amoxiclav: amoxicillin/clavulanic acid :
co-trimoxazole _____

A

Trimethoprim/sulfamethoxazole

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11
Q

Which of the following drugs does not belong to the group?

I. Omeprazole
II. Lansoprazole
III. Aripiprazole
IV. Ranitidine

A

Aripiprazole

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12
Q

Which of the following anti-TB drugs can
cause red-green color blindness

I. Rifamcin
II. Isoniazid
III. Ethambutol
IV. Streptomycin

A

Ethambutol

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13
Q

Which of the following drugs is the least
considered as prodrug?

I. Captopril
II. Enalapril
III. Ramipril
IV. Accupril
V. None of the choices

A

Captopril

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14
Q

(Enervon®) tablet contains the following
EXCEPT:

I. Nicotinamide
II. Calcium
III. Ascorbic acid
IV. Magnesium

A

Magnesium

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15
Q

The sympathetic division of the ANS
stems from_____

A

Thoracolumbar

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16
Q

Which of the following prevents the storage of the acetylcholine to terminal vesicles?

I. Vesamicol
II. Reserpine
III. Botulinum toxin
IV. Hemicholinium

A

Vesamicol

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17
Q

The following are phase II reactions EXCEPT:

I. Acetylation
II. Methylation
III. Hydrolysis
IV. Sulfonation

A

Hydrolysis

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18
Q

Monoamine oxidase is an

A

Enzyme

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19
Q

Gon went to his farm to spray pesticide on his crops. Hour later he started to experience diarrhea, vomiting, bronchoconstriction and tachycardia. He was immediately sent to the hospital for treatment. Which of drugs should be given to Gon?

A

Atropine

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20
Q

Aside from the answer in #19, what other
drug can be given to Gon?

A

DAM

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21
Q

Cookie was diagnosed to have HPN and was prescribed beta-blockers for her treatment. She has a history of asthma. Which of the ff. beta-blockers should be given to cookie?

I. Propanolol
II. Timolol
III. Metoprolol

22
Q

Andrea is going perform in the 2011 spring music festival. Hours before her performance she started to experience “stage fright”. Which of the ff. drugs can be given to manage her condition?

I. Lasartan
II. Enalapril
III. Propanolol
IV. Prazosin
V. Paracetamol

23
Q

The hydraulic equation is

24
Q

Which of the ff. are substrates of kininase II/peptidyl dipeptidase?

I. Angiotensin I
II. Bradykinin
III. Angiotensin II
IV. Angiotensin I and Bradykinin
V. Angiotensin I & Angiotensin II

Study These Flashcards
A

Angiotensin I and Bradykinin

25
Lanoxin acts on which of the following I. Na/K ATPase pump II. Na/H ATPase pump III. H/K ATPase pump IV. Na/Ca ATPase pump
Na/K ATPase pump
26
Anti-arrhythmic drugs under class 4 acts on
Ca channels
27
Which of the following are loop diuretics? I. Ethacrynic acid II. Furosemide III. Bumetimide IV. Indapamide
I and IV (Ethacrynic acid and Indapamide)
28
Andrei works as a pilot in an airline company. Which of the following antihistamines can he take? I. Fexofenadine II. Bromoheniramine III. Promethazine IV. Chlorpheniramine
Fexofenadine
29
5HT3 antagonist are used for:
Nausea and vomiting
30
Montelukast is a/an
Leukotriene pathway inhibitor
31
DOC for typical absence seizure
Ethosuximide
32
Flumazenil is
Benzodiazepine antagonist
33
Arrange the correct order of the stages of anesthesia I. Stage of excitement II. Stage of medullary depression III. Stage of surgical anesthesia IV. Stage of analgesia
IV. Analgesia I. Excitement III. Surgical anesthesia II. Medullary depression
34
Dissociative anesthetic state characterized by catatonia, amnesia, and analgesia can be produced by which drug?
Ketamine
35
Neuroleptanesthesia is produce by which drug combination?
Fentanyl, droperidol, and NO
36
Which of the following does not belong to the group? I. Lidocaine II. Mepivacaine III. Prilocaine IV. Benzocaine V. Arecholine
Benzocaine
37
What is the treatment for malignant hyperthermia?
Dantrolene
38
Which of the following antiviral drug can be used for Parkinsonism?
Amantadine
39
Jet a five year old boy is having a problem with bed wetting. What drug can be prescribed for his condition?
Amitriptyline
40
It is the dextrorotatory stereoisomer of methylated derivative of levorphanol which is used as antitussive?
Dextromethorphan
41
HMG-CoA reductase inhibitors are advised to be given during night time with the EXEPTION of _______ which can be given anytime of the day.
Atorvastatin
42
Which of the ff. vitamin can be used to lower cholesterol levels?
Niacin
43
Which of the given is considered the DMAD”s of 1st choice to treat rheumatoid arthritis?
Methotrexate
44
Isoniazid can cause the following laboratory data except?
Anemia
45
DOC for chronic gout
Allopurinol
46
A peptide hormone secreted by the posterior pituitary that participates in labor and delivery and elicits milk injection in lactating women.
Oxcytocin
47
Which of the following beta-blockers is most widely used in the therapy of thyrotoxicosis?
Propranolol
48
Marie is pregnant and was diagnosed with thyrotoxicosis. Which of the following thionamodes shoul be given to her?
PTU
49
Soluble “peakles”, ultra long acting analog
Glargine
50
Safest sulfonylurea for the elderly diabetics
Tolbutamide

Pharmacology (6 decks)

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