1. Respiratory Drugs Flashcards Preview

BDS2 BAMS Respiratory > 1. Respiratory Drugs > Flashcards

Flashcards in 1. Respiratory Drugs Deck (21):
1

Route of drug administration (3)

Inhalation (topical - applying to lung tissue via air flow)
ORal
IV

2

Drugs used in ventilation (2)

Improve airway patency
Prevent mast cell degranulation

3

Drugs used to improve airway patency (2)

Bronchodilators (B2 agonists)
Anti-inflammatories (corticosteroids)

4

Drugs used to prevent mast cell degranulation (2)

Chromoglycate
Leukotriene receptor antagonists

5

Drugs that impair ventilation (2)

B-blockers
Respiratory depressants (benzodiazepines, opioids)

6

Drugs used in gas exchange (2)

Respiratory stimulants - theophylline
Oxygen

7

Inhaled drug delivery methods (2)

MDI. - meter dose inhaler (puffer)
Breath activated device (spinhaler)

8

B-agonists can be (2)

Short acting
Long acting

9

Description of short-acting B-agonists (2)

Quick onset (2-3 mins), last 4-6hrs
Oral, inhalation, IV

10

Use of short-acting B-agonists

To treat acute bronchial constriction (asthma)

11

Examples of short-acting B-agonists (2)

Salbutamol
Terbutaline

12

Description of long-acting B-agonists (2)

Slow onset (1-2hrs), last 12-15hrs
Inhalation only

13

Use of long-acting B-agonists

To treat acute bronchial constriction
Always with inhaled steroid

14

Examples of long-acting B-agonists

Salmeterol

15

Action of anticholinergics (3)

Inhibit muscarinic nerve transmission in autonomic nerves
Bronchial dilation
Reduce mucus secretion

16

Example of anticholinergic

Ipratropium

17

Action of corticosteroids

Reduce inflammation in bronchial walls

18

Examples of corticosteroids (4)

Beclomethasone
Budesonide
Fluticasone
Mometasone

19

Compound preparations involve (2) and example

Inhaled steroid
Long-acting b-agonist
Seretide - fluticasone/salmeterol

20

Use of theophylline

Treat asthma and COPD

21

Actions of theophylline (4)

Relax bronchial smooth muscle
Increase heart muscle contractility and efficiency
Increase HR
Increase BP, renal blood flow and anti-inflammatory effects