Henoch-Scholein Purpura (HSP)

Question 1

pathogenesis

Answer 1

Acute IgA-mediated disorder
generalized vasculitis involving the small vessels of the
o	skin
o	GI tract
o	kidneys
o	joints
o	rarely the lungs
o	rarely CNS

Question 2

who gets it?

Answer 2

commonly children

commonly a history of URT infection predates the symptoms by a few weeks

Question 3

how does it present?

Answer 3

purpuric rash over the buttocks & lower limbs
abdominal pain
vomiting
joint pain

Question 4

how is it managed?

Answer 4

self-limiting condition
no specific treatment
settles over weeks-months