10.1

Question 1

First Gap

Answer 1

Cell grows, prepare for DNA replication.

Question 2

Synthesis Phase

Answer 2

Replicate DNA. Cell will have two copies of DNA.

Question 3

Second Gap

Answer 3

Cell continue to grow and prepare for cell division.

Question 4

G1 Checkpoint.

Answer 4

Not damage DNA, sufficient resourse.

Question 5

S checkpoint

Answer 5

No error during replication.

Question 6

G2 checkpoint

Answer 6

DNA good, chromosome set complete. Enough cell components.

Question 7

M checkpoint

Answer 7

All sister chromatids attach to the mitotic fibers

Question 8

Why will cell go to G0?

Answer 8

Not enough resource or time to differentiate.

Question 9

What cell always are in G0?

Answer 9

Neurons and muscles cells.

Question 10

Stimulating Proteins are:

Answer 10

Move the cell into the next stage of the cell cycle, growth factors, APC/C, cyclin-dependent kinases (CDKs), cyclins and proto-oncogenes

Question 11

Inhibitory Protein are:

Answer 11

prevent activation of CDK-cyclins
MAD, Stop the cell from moving past a checkpoint if it does not meet requirements, BRCA1, ATM, Rb, tumor suppressor genes, and p53

Question 12

Density Dependent Inhibition:

Answer 12

Cell get close, they stop dividing.

Question 13

Anchorage Dependence

Answer 13

Need to attach to certain cell or proteins to divide.

Question 14

Which comes first? Put in order.
A. Cylcin/cdk complexes form to activate cdk
B. Growth factor are released
C. cdk phosphorylates target enzyme and trigger next phase of the cell cycle.
D. Cylcin levels increase.

Answer 14

A=3
B=1
C=4
D=2

Question 15

Proto-oncogenes

Answer 15

Code for stimulate proteins. Become oncogenes when mutated. If one is permanently on, can cause cancer.

Question 16

Tumor suppressor genes.

Answer 16

Code for inhibitory proteins. If both off, can cause cancer. example p53. P53 stop S phase when damage DNA.