Malaria, Schisotomiasis

Question 1

First line vs uncomplicated and severe plasmodium falciparum

Answer 1

Artemether-Lumefantrine (AL) combination
Alt: quinine (QN) + tetracycline or doxycycline or clindamycin x7 days
(QN+T/D/C x 7 days)

Question 2

Recommended prophylaxis

Answer 2

Atovaquone-proguanil
Doxycyline
Mefloquine

Question 3

Atovaquone-proguanil dosing

Answer 3

Take 1 tablet daily (atovaquone 250mg + progaunil 100mg)

Start 1-2 days before entering the malarious area, ccontinue daily during stay and continue for 7 days after leaving

Question 4

Doxycyline dosing

Answer 4

Take 1 tablet daily of 100mg

Start 1 day vefore entering malarious area, continue daily during stay, continue for 4 weeks after leaving

Question 5

Mefloquine dosing

Answer 5

Tak 1 tablet of 250mg (228mg base) once a week

Start 1-2 weeks before entering the malarious area, continue weekly during stay, continue for 4 weeks after leaving

Question 6

Remarks on malaria in the Philippines

Answer 6

We have chloroquine-resistant malaria

Question 7

Prophylaxis for pregnant patients

Answer 7

DOC: CHLOROQUINE

MEFLOQUINE for those with chloroquine-resistant malaria e.g. Philippines