Congenital, neonatal and perinatal infection Flashcards
What is TORCH?
Set of 5 diseases that are the classic congenital infections -toxoplasmosis, OTHER (Syphilis, Parvo, VZV, HIV, HBV) rubella, CMV, Herpes
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Management of congenital toxoplasmmosis (paeds)
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child -1st line pyreamethamine _ sulfadine
with pred
Management of congenital syphilis(paeds)
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IM benzathine peniciliin
Management of congenital parvovirus (paeds)
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Intrauterine -blood transfuse if foetal hydrops
Infant -self limiting
Management of congenital Vzv (paeds)
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IV acyclovir,
neontatl ophtalmic exam
monitor until 28 day post maternal infect
Management of congenital HIV (paeds)
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Cord clamped as fast as possible and immediate bath
Zidovuline monotherapy for 2-4w (low risk), or 4w of PEP combination
No breastfeeding
All immunisation
PCR at 6, 12 weeks should have passive IgG until 6m
Management of congerintal Hep B (paeds)
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Acute maternal -not dangerous
chronic HBV - can lead to IUGR and prematurity
HBV vaxx (for mum and child) Mother- tenofir dosproxil -breastfeeding FINE Baby -passive immune through HBV IV and HBV vax 12h after birth
Management of congenital Rubella (paeds)
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Refer child to feotal medicine and notify HPU
no treatment -support
Cardiac scans and screening tests
Management of congenital CMV (paeds)
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IV ganciclovir
Management of congenital HSV (paeds)
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Aciclovir if neonate exposed on delivery
