Hepatitis Flashcards
Hepatitis
inflammation of liver and can occur in an acute or chronic setting
causes
viral autoimmune non-alcoholic liver disease alcohol drugs
Hepatitis A
faecal-oral route
anal-oral sex
vaccine present
RF:
undercooked meat/unclean water
symptomatic management
Hepatitis B
blood or bodily fluids
mother to baby
vaccines present
most common
must inform government
Hepatitis C
blood or bodily fluids
Vaccine present
must inform government
Hepatitis D and E
no vaccine present
less common
pig meat is a risk factor for Hep E
Hepatitis B investigation
HbsAg - active infection
HbeAg - how infective
HbsAb - vaccine or exposure
HbcAb - past or current infection (IgG - past infection, IgM - active infection)
management of hepatitis B
interferon-alpha
tenofovir
previous immunisation of Hep B
HbsAb positive, HbcAb negative
affected and recovered from Hep B
HbcAb (IgG) positive, HbsAg negative, HbsAb positive
chronic carrier of Hep B
HbcAb (IgM) postive, HbsAg positive, HbsAb positive
types of hepatitis C and management
acute - HCV-RNA +Ve
previous - HCV-RNA -ve, anti-HCV +ve
chronic - HCV-RNA +ve, anti-HCV +ve
anti-virals for chronic
general investigations
FBC
LFT - high AST/ALT, lower rise in ALP
autoimmune hepatitis features
occurs commonly in young females
family history of autoimmune condition
jaundice
hepatomegaly
amenorrhoea
fever
management:
steroids
immunosuppressants - azathioprine
what do you do if you are exposed to hepatitis B before being fully vaccinated
give an accelerated hep B vaccine + immunoglobulin
