Nitroprusiato de Sodio Flashcards

1
Q

Mecanismo de acción

A

Donador de óxido nítrico.

Producen vasodilatación.

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2
Q

Indicaciones clínicas

A

Crisis Hipertensivas
Falla cardiaca congestiva

Acción inmediata

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3
Q

Farmacocinética relevante

A
A: IV  F: 100%
D: 
    PB y VD: No
M: Eritrocitos --> Cianometahemoglobina.
Produce cianuro y tiocianato.
E: Renal
   V1/2e: 2 min
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4
Q

Reacciones adversas

A

Hipotensión
Necrosis epidérmica ´tóxica
Acidosis metabólica
-Envenenamiento-

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5
Q

Interacciones relevantes

A

Sildenafil

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6
Q

Categoría en el embarazo

A

C

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7
Q

Precauciones y contraindicaciones

A

Contrainidcado en: Falla Cardiaca Aguda.

Produce envenenamiento en altas dosis

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