100. Bradsot of sheep and Köves-disease of swine.

Question 1

Occurrence and ethiology of Bradsot?

Answer 1

Occurrence:

Northern Europe

x Etiology:

• C. septicum
• Late autumn-winter,
• winter pasture - colder,
• 1) Summer pasture Æ winter
• 2) Soil contaminated frozen feed (potato, turnip), sudden appearance

Question 2

Pathogenesis and clinical signs of bradsot?

Answer 2

Pathogenesis:

• infection PO (soil contaminated frozen feed)
• Æ mucous membrane of stomach (rennet)
• Æ damage MM
• Gas gangrene in wall of stomach, duodenum

Clinical signs:

• sudden onset,
• General:
• depression,
• teeth grinding,
• pulmonary and heart failure

Question 3

Pathology and diagnosis?

Answer 3

Pathology:

• Rennet,
• proximal small intestine (thickened, hemorrhagic - serous, necrosis of MM),
• fluid in abdominal and thoracic cavity

x Diagnosis:

• signs and PM lesions
• o Detection of agent:
• microscopy,
• culture (found in PM too),
• IF,
• PCR

Question 4

Treatment and prevention, control?

Answer 4

Treatment:

• fast course,
• no time

x Prevention, control:

• prevention of predisposing effects
• vaccines (theoretically have vax, but better to prevent!)

Question 5

Koves disease?

Answer 5

Occurrence: rare

Etiology: C. septicum

Indicator disease (hemorrhages in the stomach ʹ something in background like;

1. Classical swine fever,
2. TGE,
3. mycotoxins,
4. esophageal ulcer

Clinical signs:

sudden death

Pathology:

stomach wall thickend,

rubber-like,

serous ʹ gas bubbles sometimes in muscles

Diagnosis:

detection of agent (staining, isolation of agent), identification of the predisposing factors,

DDX!

Prevention, control:

prevention of predisposing effects,

vaccination is not used