22: NMJ and Skeletal Muscle Disorders Flashcards
1
Q
two major sx of dz of NMJ
A
painless weakness + fatigue
2
Q
satellite cells
A
small pool of stem cells that contribute to muscle regeneration after injury
3
Q
myofiber types and how theyre arranged in skeletal muscle
A
type I and II, arranged in a checkerboard pattern
4
Q
what determines muscle fiber type?
A
the signal received by innervating motor neurons
5
Q
type of atrophy caused by prolonged corticosteriod use
A
type II fiber atrophy
6
Q
high CK in blood
A
marker of muscle damage
7
Q
two signs of proximal weakness
A
difficulty rising from chair + climbing stairs
8
Q
what gene is associated with malignant hyperthermia
A
RYR1 gene
9
Q
major condition we learned about that causes floppy baby syndrome
A
spinal muscular atrophy
