30: RA Flashcards
specific HLA linked to RA
DRB-4
RA in pregnancy
improves while pregnant, flares 4-6wks post-partum
what way does the wrist tend to deviate in RA
radial deviation
pyoderma gangrenosum
tender red/purple papules -> necrotic, non-healing ulcers in RA
lung things that can happen with RA
pleuritis (MC), nodules, ILD, Caplan syndrome (nodules after coal/silica exposure), pulmonary fibrosis
what is the eye dryness test for sjogren’s called?
Schirmer’s test
Felty’s syndrome
RA + fever, splenomegaly, pancytopenia
C spine in RA
erosion of odontoid process, weak transverse ligament
when else can RF be positive besides RA?
- 1-4% of healthy elderly pts
- viral hepatitis
- CTD, SLE, polymyositis, Sjogren’s, CREST
- lymphoma, myeloma
- Tb, mono, syphylis, sarcoid
two ways steroids are used in RA
- bridge therapy before DMARDs
2. flare ups
toxicities of all biologics
- increased infection
- Tb reactivation
- neoplasias
- MS
- autoimmune dz
dactylitis
swelling of fingers/toes
enthesitis
ligament or tendon attachment to bone due to inflammatory changes
spondylitis
inflammation of a vertebrae
spondylolisthesis
anterior displacement of a vertebral body relative to the adjacent
