Campylobacter Flashcards

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1
Q

Two kill campylobacter, what temp do you have to cook to

A

An internal temp of 70C for two minutes

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2
Q

What are three ways campylobacter can be transmitted

A
Through consumption of undercooked or contaminated food
OR
Via contact with animals
OR 
Person-person (fecal-oral route)
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3
Q

What time of year do campylobacter infections peak

A

In the summer

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4
Q

What are some reasons behind the peak season of campylobacter

A

Ambient temp, human behaviour, seasonal variation in chicken flocks, flies are more active (can carry it)

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5
Q

What is the most common type of campylobacter, and what are its reservoirs and symptoms of disease

A

C. jejuni
Poultry, pigs, dogs, cats, birds, insects
Gastroenteritis, septicemia, meningitis, abortion

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6
Q

How many gastroenteritis cases are caused by C. jejuni

A

90% (rest C. coli)

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7
Q

What is the most extensively studied extraintestinal manifestation associated with campylobacter infection

A

GBS and Miller Fisher syndrome

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8
Q

What is the main difference between MFS and GBS

A

The first nerve groups to be affected in MFS are in the head, thus affecting eye muscles and balance (paralysis in GBS starts in legs

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9
Q

What are some clinical manifestations of different campylobacter infections

A

Gastro, brain abscess, periodontitis, GBS/MFS, IBD, esophageal disease, bacteremia/septicemia

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10
Q

What are some factors involved in the molecular pathogenesis of campylobacter

A

Motility, adhesion, protein secretion/invasion, toxin production, actin polymerization and endocytosis

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