DVT and VTE

Question 1

Give some examples of risk factors for VTE

Answer 1

• Immobility
• Surgery
• Oestrogen (HRT/COCP)
• Pregnancy
• Malignancy
• Long haul flight
• Thrombophilia

Question 2

Give three examples of thrombophilias?

Answer 2

• Antiphospholipid syndrome
• Factor V Leiden
• Protein C or S deficiency

Question 3

In a case of suspected DVT/PE, which scoring system is used to guide further investigation?

Answer 3

Wells score

Question 4

What is the diagnostic investigation for DVT?

Answer 4

USS doppler

Question 5

What is the diagnostic investigation for PE?

Which investigation can be used as an alternative?

Answer 5

CTPA

V/Q scan can be used as an alternative (e.g. pregnancy, contrast allergy)

Question 6

Which blood test can be done to exclude DVT/PE?

Answer 6

D-dimer

Question 7

What is the first line pharmacological management of DVT/PE?

Answer 7

DOAC, e.g. apixaban, rivaroxaban

Question 8

What is Budd-Chiari syndrome?

How does this present?

Answer 8

Where a blood clot (thrombosis) develops in the hepatic vein, blocking outflow of blood from the liver causing acute hepatitis

Presents with classic triad of symptoms:

• Abdominal pain
• Hepatomegaly
• Ascites