Pulmonary 1

Question 1

Pts w/ CNS malignancy are at particularly high risk of this opportunistic PNA

Answer 1

PJP

Question 2

Pts w/ T-cell directed therapies for transplant are at particularly high risk of this opportunistic PNA

Answer 2

CMV pneumonitis

Question 3

Tx for SLE DAH

Answer 3

IV corticosteroids + cyclophosphamide (or rituximab or MMF)

Question 4

Ppeak is the sum of these 3 pressures

Answer 4

Flow-related, elastance-related, and PEEP

Question 5

The PROSEVA study demonstrated a decrease in _____ in severe ARDS with the early application of prolonged prone-positioning sessions (minimum 16 h/day).

Answer 5

28-day and 90-day mortality

Question 6

Why mechanical ventilation may cause a hypovolemic pt to crump

Answer 6

Reduced venous return to heart (due to PPV)

Question 7

Effect of prone position on heart chamber size/shape

Answer 7

Rightward shift of interventricular septum

Question 8

TX for mod-severe blastomycosis

Answer 8

Amphotericin B

Question 9

Tx for mild blastomycosis (or after acute Tx of severe)

Answer 9

Itraconazole

Question 10

What was the PEITHO trial?

Answer 10

heparin vs. heparin + thrombolysis for submassive PE w/ Rt Ht strain

Question 11

Was there a significant difference in mortality + hemodynamic instability in PEITHO trial? Why?

Answer 11

yes; driven by hemodynamic instability

Question 12

Pts treated with heparin + thrombolytics in PEITHO trial were at significantly higher risk of _____.

Answer 12

extracranial bleeding