Pharm 1 - Δ-Δ, Poisoning

Question 1

Delta-delta (delta gap)

Answer 1

ΔAG - ΔHCO3

Question 2

Delta gap indicating concomitant non-AG metabolic acidosis

Answer 2

< -6

Question 3

Delta gap indicating concomitant non-AG metabolic alkalosis

Answer 3

> 6

Question 4

RSI med that can cause malignant hyperthermia

Answer 4

Succinylcholine

Question 5

Rx for malignant hyperthermia

Answer 5

Dantrolene

Question 6

Rx for cyanide (first-line)

Answer 6

Hydroxocobalamin

Question 7

Drug type / mechanism of sarin

Answer 7

Anticholinergic

Question 8

Rx for organophosphates

Answer 8

Pralidoxime

Question 9

Mechanism of action of organophosphates

Answer 9

inhibition of acetylcholinesterase (CHOLINERGIC)

Question 10

Symptoms of cholinergic toxicity

Answer 10

DUMBBELS (diarrhea, urination, miosis, bronchospasm, bradycardia, lacrimation, salivation)

Question 11

Methylene blue treats

Answer 11

Methemoglobinemia (and vasoplegia)

Question 12

Tx for ethylene glycol or methanol poisoning

Answer 12

Fomepizole and dialysis

Question 13

Rx for cyanide (second-line)

Answer 13

sodium nitrite, sodium thiosulfate