Anti-emetics

Question 1

Which anti-emetic is preferred in Parkinson’s patients?

Answer 1

Domperidone is first line as it does not cross the BBB, therefore avoids extra-pyramidal side effects

Question 2

Which anti-emetics are preferred in pregnant women?

Answer 2

Cyclizine is first line
Promethazine is second line
Ondansetron is not licensed

Question 3

Which anti-emetic is typically used post-operatively?

Answer 3

Ondansetron (do not use if prolonged QT) or cyclizine if caused by opioids or anaesthetic
Prochlorperazine is an alternative

Question 4

Which antiemetics are used for chemotherapy related nausea?

Answer 4

Ondansetron with dexamethasone

Alternatively can use prochlorperazine

Question 5

Which anti-emetics are used in palliative care?

Answer 5

Levomepromazine or haloperidol

Question 6

Which anti-emetic is used in GI or biliary disease?

Answer 6

Metoclopramide