Obstructive Therapeutics Flashcards

1
Q

what is the management for intermittent asthma?

A

SABA

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2
Q

what is the management for mild, persistent asthma?

A
  1. SABA

2. ICS

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3
Q

what is the management for moderate/severe asthma?

A
  1. SABA
  2. ICS
    • LABA/LAMA or theophylline
  3. oral steroid
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4
Q

name an inhaled steroid

A

beclomethasone

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5
Q

how should ICS be given in COPD?

A

as an ICS/LABA/LAMA

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6
Q

name a cromone

A

cromoglycate

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7
Q

what is the MoA of cromoglycate?

A

mast cell stabiliser

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8
Q

what disease is cromoglycate used for?

A

asthma

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9
Q

name a leukotriene receptor antagonist

A

montelukast

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10
Q

name an anti-IgE monoclonal antibody for asthma

A

omalizumab

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11
Q

how do beta agonists work?

A

stimulate bronchial smooth muscle beta 2 recpetors

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12
Q

name a SABA

A

salbutamol

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13
Q

name a bi daily LABA

A

salmeterol

formoterol

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14
Q

name some once daily LABAs

A

indacaterol
vilanterol
oldaterol

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15
Q

how do muscarinic antagonists work?

A

block post junctional end plate M3 receptors

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16
Q

name a SAMA

A

ipratropium

17
Q

name a LAMA

A

tiotropium

18
Q

what muscarinic antagonost can be used in asthma?

A

tiotropium

19
Q

what methylxanthine can be given orally for maintenance therapy?

A

theophylline

20
Q

what methylxanthine can be given for acute attacks?

A

IV aminophylline