Molar Pregnancy Flashcards
Another term for molar pregnancy?
Gestational trophoblast disease
What is molar pregnancy?
-Describes the proliferative conditions of placental tissue
Types of molar pregnancy?
2 types
-Complete and partial hydatiform mole
What is choriocarcinoma?
Malignant tumour of trophoblast and is fetal in origin
Are molar pregnancies common?
NO
Very rare
What race would molar pregnancies be more common in?
Asia
SE Asia
What is a complete mole?
Occurs when an ovum lacking its nucleus is fertilized by 1 sperm (that duplicates its DNA) or 2 sperm resulting in a diploid cell but with only paternal contribution
-There is no fetus
What happens to uterus in molar pregnancy?
Uterus is filled with grape like cluster pf cysts of varying size
When does a partial mole occur?
When an ovum is fertilized by 1 sperm (that duplicates its DNA) or 2 sperm resulting in triploidy
-Malformed/non-viable foetus and overgrowth of placental tissue
Presentation of molar pregnancy?
- Hyperemesis, hyperthyroidism, early onset pre-eclampsia
- Varied bleeding and occasional passage of grapelike tissue
- Size of uterus on fundal palpation is bigger than that expected for gestation length
Management of molar pregnancy?
-Uterine evacuation surgery is done and tissue is sent for histology to ascertain the type of mole
-Registration and follow up
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Risk of a complete mole developing into a choriocarcinoma?
2.5% risk
What is a molar pregnancy?
Abnormal form of pregnancy in which a non-viable fertilized egg implants in the uterus (or tube)
Characteristic of molar pregnancy?
Swollen chorionic villi
