Hyperemesis Gravidarum

Question 1

What is hyperemesis gravidarum?

Answer 1

-Vomiting and nausea in the first trimester is common and usually self-limiting
HOWEVER
If excessive, protractive and quality of life altering= Hyperemesis gravidarum

Question 2

Presentation of hyperemesis gravidarum?

Answer 2

-Prolonged and sever N&V
-Dehydration, ketosis, electrolyte and nutritional disturbance
-Wt loss
-Hypotension
-Emotional instability
-

Question 3

Hyperemesis gravidarum is what type of diagnosis

Answer 3

Diagnosis of exclusion

Question 4

Management of hyperemesis gravidarum?

Answer 4

Rehydration, IV nutritional and electrolyte replacement

1st line anti-emetic = cyclazine or promethazine

Thiamine vitamin supplements

Steroid used in severe recurrent cases

Thromboprophylaxis needed as increased blood risk

Question 5

1st line anti-emetic for hyperemesis gravidarum?

Answer 5

Cyclizine