Introduction & Review Flashcards
1
Q
Rank order of female cancer deaths/year:
Breast Ovarian Bowel Pancreas Lung
A
Lung Breast Bowel Pancreas Ovarian
2
Q
Rank order of male cancer deaths/year: Breast Prostate Bowel Pancreas Lung
A
Lung Prostate Bowel Pancreas Breast
3
Q
What was the biggest factor in lung cancers mortalities decreasing?
A
Smoking
4
Q
What was the single largest contributor to cervical cancer mortailites decreasing?
A
Pap smear- Detection
HPV Vaccine- Prevention
5
Q
What caused stomach cancer mortailties to decrease?
A
Better food storage- Refrigeration, better standards lead to reduced infections
6
Q
What type of mutations can affect a whole organism and is passable to offspring?
A
Germ Line Mutations
7
Q
What type of mutation affects inital cell and its lineage and is not passable to offspring?
A
Somatic Mutations
8
Q
Epigentetic mechanism for suppression of tumour suppressor gene?
A
Hypermethylation of tumour supressor gene.
Hidners transcription factor binding
