Biomarkers, Off-target Toxicity & Targeted therapies

Question 1

What are the classes of biomarkers?

Answer 1

Predisposition
Early Detection
Prevention
Diagnosis
Therapy
Monitoring

Question 2

What are the benefits of liquid biopsy?

Answer 2

It is minimally invasive procedure
It provides tumoural information to guide therapy
It contains tumoural content, such as circulating tumour cells, cell-free nucleic acids, proteins and extracellular vesicles, into the circulation and these biomarkers are reported to cross the blood-brain barrier