giardiasis, histolytic, visceral leishmanias Flashcards

1
Q

clinical symptoms L.donovani

A

fever
splenomegaly
pancytopenia

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2
Q

morphological forms of l.donnovani

A

amastigote (human) promastigote (sandfly)

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3
Q

species of leishmania

A

l. donnavani donnovani - inida
L. Infantum - europe
L. chagasi -south america

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4
Q

cells affected in l.donnovani

A

RES+ macrophages

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5
Q

treatment for L. donovani

A

gucantime, amphotreicin B,pentamidine, miltefosine , allopurinol

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6
Q

is visceral leishmaniasis a zoonosis or anthroponosis

A

zooinos

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7
Q

name of disease caused by e.histolytica

A

amoebiasis

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8
Q

different forms of e.histolytica in humans

A

intesinal : diarrhea,

extraintestinal: liver abscess,fever

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9
Q

trophozoite form of e. histolytica

A

forma magna - invasive form invades the mucosa

forma minuta- aymptomatic, commensal

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10
Q

infective form of e.histolytica

A

cyst (quadrinucleate)

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11
Q

target of e. histolhyitca

A

large colonn

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12
Q

treatment for e.histolytica

A

metronidazole/tinidazole- relief of symptoms, kill trophozoites but not cysts
iodoquinol/paromycin- kill cysts

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13
Q

important severe complication of histolyitca

A

toxic megacolon

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14
Q

IP e.histolyitca

A

intestinal l- 1-4 weeks

extraintestinal - variable

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15
Q

IP e.histolytica

A

intestinal l- 1-4 weeks

extraintestinal - variable

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16
Q

where does lambia live

A

duodenum and upper jejanum

17
Q

infective form of lamblia

A

cyst

18
Q

IP of lamblia

A

2 weeks

19
Q

which parasite has a falling leaf pattern on microscopy

A

G.lamblia

20
Q

treatment for giardiasis

A

metronidazole\tinidazole

21
Q

naegleriasis causative agent

A

naegleria fowleri

22
Q

mode of entry of naegleria

A

nose- CNS (olfactory nerve)

23
Q

fatal consequence of naegleria

A

PAM primary amoebic meningoencephalitis

24
Q

morphological forms of naegleria

A
  1. cyst 2. trophozoite 3. flagellated form
25
Q

what kind of water does naegleria

A

freshwater lakes streams

26
Q

treatment for naegleriasis

A

not optimal, just use a combo

antifungals, miltefosine, amphotericin B

27
Q

acanthamebiasis leads to

A

GAE

28
Q

Treatment for acanthamoebiasis

A

corneal debridement
keratoplasty
topical chlorhexidine

29
Q

Mao humans get visceral leishmanias

A

bite of sandfly and sanfly regurgitates promastigoTes into the wound this is because they have difficulty sucking blood as they are blocked by the enormous numbers of promastigoTes

30
Q

causes of anemia in kala azhaar

A

splice sequestration
Bm infiltration
autommune hemolysis
hemorrgae

31
Q

morphology of leishamani

A

flagellete protozoa

32
Q

which type of leishmania is not a zooinot

A

l. donnovani the Indian type