cell mediated immunity Flashcards
th2 activate ?
B cells
th1 activate
other T cells and macrophages
how do T cells recognize MHC + Ag?
T cell receptor
what part of T cell is responsible for signaling / activating T cell?
CD3
which cells involved in cell mediated immunity?
Tc NK MQs Granulocytes ADCC
how do Tc kill target cells?
using perforin which makes holes in the target cells membrane
using granzymes
using TNF alpha/ beta and IFN gamma
what together from the Tc trigger apoptosis?
granzymes and cytokines
what is important in inhibiting tumors?
NK cells
true or false. NK cells don’t have TCR.
true they have NKR
what kills cancer cells and virus cells?
NK and Tc
what cells are involved in ADCC
MQs
NK cells
Neutrophils
Fc receptors bind to
Ab on bacteria
Complement receptors bind to
C on bacteria
what are the 3 cytotoxic cells?
Tc
NK
ADCC (K) cells
sometimes microbes hide in MQs for years / long periods of time and they do this by inactivating it. What cell recognizes that this and activates the MQs?
Th1
