lymph node ( anatomy) Flashcards

1
Q

what are the two routes lymphocytes enter lymph node?

A

afferent lymphatic vessels (10%)

HEVS in deep cortex by process called diapedesis (90%0

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2
Q

how many efferent vessels does each node have?

A

one

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3
Q

lymph circulation in lymph node

A

afferent –> subcapsular sinus –> trabecular sinus –> deep cortex –> medullary sinus –> leave node by efferent vessel

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4
Q

HEV have what?

A

aquaporin 1

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5
Q

sub scapular sinus + superficial cortex and trabecular are all made of what?

A

dense CT

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6
Q

storm of lymph node is made of what?

A

reticular fibers and cells

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7
Q

what cells are found in the germinal center?

A

reticular cells = secrete collagen
follicular dendritic cells
B lymphocytes

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8
Q

right upper quadrant drains into

A

right lymphatic duct

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9
Q

rest of body drains into

A

thoracic duct

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10
Q

venous angles between what two veins?

A

internal jugular and subclavian

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11
Q

whats the first line of defense?

A

diffuse lymphatic tissue

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12
Q

where is diffuse lymphatic tissue found

A

mucous membranes
git
respiratory tract
geniturinary tract

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13
Q

what cells does the mucosa / lamina propria contain?

A

lymphocytes
fibroblasts
eosinophils
plasma cells

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14
Q

palatine tonsils are covered by

A

stratified squamous nonkeratinized epithelium

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15
Q

tonsilar crypts are remnants of what?

A

2nd pharyngeal pouch

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16
Q

peyers patches

A

aggregated lymphatic nodules found in the ileum

17
Q

t lymphocytes are mainly found in the

A

deep cortex but a little found in superificicial around germinal centers

18
Q

b lymphocytes are found in the

A

germinal centers in the superficial cortex

19
Q

CD3

A

T cell marker

20
Q

CD20

A

B cell marker

21
Q

reticular cells synthesize

A

type iii collagen and grout substance

22
Q

dendritic cells

A

APCs
found with t lymphocytes = deep cortex
high level of MHC II
derived from bm