Osteoporosis Flashcards

1
Q

Fx mas clmunes

A

Cadera
Colles
Vertebras t

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2
Q

Valores de densimetria osea

A

Menos de - 2.5

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3
Q

Farmacos que ocasionan

A

IBP, anticoagulantes, h tiroideas, ISRS

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4
Q

Fisiopato

A

RANK-l activa a osteoclastos y aumenta la resorcion.
Hay baja produccion de OPG debido a la poca concentra de estrogenos. Por tamto, los osteoclastos siempre estaran activos.
Tambien la esclerostina se pega a los psteoblastos y evitan que produzcan hueso suficiente

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5
Q

Manif clinicas

A

Fx de baja emergia
Cadera sangra
Deformidad de costillas por fx vertebrales

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6
Q

FR modificables

A

Peso bajo
Def. Estrogenica, bajo consumo de clacio, caidas recurremtes, inactividad

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7
Q

Dx

A

BH (hb y VSG)
QS (evalua fx renal antes de dar tx)
Niveles de Vit.D
Electrolitos ( descartam hiperparati, anomalias de ca y p)
Densitometria osea

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8
Q

Tx

A

No farmacológicos ( ejercicios de resistencia, nutrición)

Farma ( Bisfosfonatos, evitar en falla renal grave. (RISENDRONATO, UNICO EN IR)) ZOLENDROMATO UNICO EN HIPERCALCEMIA (5MG/AÑO)

EA (esofagitis, necrosis y ulceras

NO DAR FARMA EN <30 ml de depuracion renal

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