12. interstitielle Lungenparenchymerkrankungen Flashcards

(28 cards)

1
Q

(ILD)

Ätiologien (Häufigkeit)

A
  • 50% IIP
  • 50% sekundär
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2
Q

(ILD)

IIP

A

Idiopatische Interstitielle Pneumonie

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3
Q

(ILD)

häufigste IIP

A

IPF

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4
Q

(ILD)

IPF

A

Idiopatische Pulmonale Fibrose

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5
Q

(ILD)

sekundäre Ätiologien (3)

A
  • medikamentös
  • inhalative Noxen
  • systemische Erkrankungen
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6
Q

(ILD)

Pathophysiologie

A

Lungenfibrose

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7
Q

(ILD)

Komplikationen (2)

A
  • Cor pulmonale
  • respiratorische Insuffizienz
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8
Q

(ILD)

Leitsymptome (2)

A
  • progrediente Belastungsdyspnoe
  • trockener Reizhusten
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9
Q

(ILD)

Inspektionsbefunde (2)

A
  • Trommelschlägelfinger
  • Uhrglasnägel
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10
Q

(ILD)

Auskultationsbefund

A

Sklerosiphonie

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11
Q

(ILD)

Sklerosiphonie

A

beidseitig basales inspiratorisches Knisterrasseln

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12
Q

(ILD)

Labordiagnostik

A

BGA

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13
Q

(ILD)

BGA: Befund

A

↓ pO2

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14
Q

(ILD)

Bildgebung: Planung (2)

A
  1. Röntgen-Thorax
  2. HR-CT-Thorax
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15
Q

(ILD)

HR-CT

A

High-Resolution-CT

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16
Q

(ILD)

radiografischer Befund

A

retikuläre Zeichnungsvermehrung

17
Q

(ILD)

tomografische Befunde (2)

A
  • Honigwabenmuster
  • Bronchiektasen
18
Q

(ILD)

apparative Diagnostik (2)

A
  • Spirometrie
  • BAL mit Bipsie
19
Q

(ILD)

Spirometrie: Befund

A

restriktive Ventilationsstörung

20
Q

(ILD)

restriktive Ventilationsstörung: Charakteristik (3)

A
  • ↓ Vitalkapazität
  • ↓ ↔︎ FEV1
  • ↔︎ Tiffeneau-Index
21
Q

(ILD)

Therapieplanung

A
  1. nicht-medikamentös
  2. medikamentös
22
Q

(ILD)

nicht-medikamentöse Therapie der Wahl

A

pulmonale Reabilitation

23
Q

(ILD)

medikamentöse Therapie der Wahl

A

Glucocorticoide + Antifibrotika

24
Q

(ILD)

Glucocorticoide: Indikation

A

bei Exazerbationen

25
(ILD) Antifibrotika: Indikation
bei schweren Verläufen
26
(ILD) Antifibrotika: Wirfstoffe (2)
- Pirfenidon - Nintedanib
27
(ILD) Pirfenidon: Klasse
TGF-β1-Antagonist
28
(ILD) Nintedanib
TKI