Proteus Flashcards
what is most potent proteus disease
proteus mirabilis
ich proteus are very rare
proteus penneri
proteus vulgaris
gram
shape
lactose fermenter?
TSI
urease
smell? and why
motility?
gram negative
rod
lactose non fermenter
H2S gas on TSI
urease positive
ammonia smell – converts urea to ammonia
motile with peritrichous flagella
types of motility
swarming – solid media
swimming – liquid media
what are dienes lines
differentiate identical and different strains of proteus on agar
immune evasion
O antigens
flagellin variants
ZapA metalloproteases
can it infect the environmet
yes
feces, sewage, manure, polluted soil, water, plants
what does it indicate
fecal pollution in water and soil
surface structures
fimbria
flagella
LPS
O and capsular antigens
biofilm
invasiveness – internalization into host cells
enzymes
urease
protease
deaminase
toxins
hemolysin
proteus toxic agglutinin (Pta)
zinc and phosphate transport systems
siderophores
what is the most important enzyme of proteus
urease
most potent virulence factors of proteus
flagellar elongation
urease
where is urea converted to ammonia and what does it cause
urease converts urea to ammonia in urine
alkaline urine pH, kidney stones
p mirabilis stone types and infection
struvite renal stones
UTI
