Klebsiella Flashcards
which ones are members of ESKAPE
klebsiella aerogenes
klebsiella pneumoniae
important klebsiella
k aerogenes
k pneumoniae
k oxytoca
what kind of resistance
carabenem
gram
lactose fermenter?
motility
TSI
urease
oxidase
catalase
gram negative
lactose fermenting
non motile – no H antigen
CO2 gas on TSI
urease positive
oxidase negative
catalase positive
does it have LPS
yes – O antigen
describe colonies
highly mucoid due to thick capsule
hypercasulated k pneumoniae characteristics
hypervirulent
additional siderophores
hyper mucoid
more dangerous
how to detect hypercapsulated k pneumoniae
string test
what is the mucoid capsule and what is its function
organized glycocalyx
ability of klebsiella to be resistant
virulence
capsular slime layer
LPS – evade serum killing factors
adherence type I fimbriae
biofilms
outer membrane protein – protect from antimicrobials
siderophores
urease – growth in urinary tract
colibactin toxin
multidrug resistance – 5 different plasmids
habitat
mouth
skin
vulva
teats
colon
intestine
bowel
respiratory tract
feces
soil
water
sewage
plants
why is klebsiella super resistant to diverse antimicrobials
contains 5 plasmids
why is klebsiella super resistant to diverse antimicrobials
why is klebsiella the leading trafficker of multidrug resistant encoding plasmids
contains 5 plasmids
what habitat does klebsiella love
intestines
tranmission
all from own flora
feco oral route – can live in food
