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IBI Test I > RNA viruses > Flashcards

RNA viruses Flashcards

1
Q

what kind of genetic material is in the reovirus?

A

DS linear RNA

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2
Q

is the reovirus positive or negative sense?

A

positive

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3
Q

is the reovirus segmented?

A

yes, 10-12 segments

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4
Q

is the reovirus enveloped?

A

no

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5
Q

what kind of genetic material is in a picornavirus?

A

ss linear RNA

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6
Q

is the picornavirus negative or positive sense?

A

positive

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7
Q

is the picornavirus enveloped?

A

no

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8
Q

poliovirus is a member of

A

picornavirus

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9
Q

rhinovirus is a member of

A

picornavirus

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10
Q

what kind of genetic material is in favivirus

A

ss linear RNA

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11
Q

are faviviruses enveloped?

A

yes

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12
Q

are flaviviruses positive or negative sense?

A

positive

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13
Q

faviviruses are caused by

A

zoonotic spread

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14
Q

what type of genetic material is in orthomyxovirus?

A
  • sense ss linear RNA
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15
Q

where do orthomyxoviruses replicate?

A

nucleus

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16
Q

how many segments do orthomyxoviruses have?

A

8

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17
Q

are orthomyxoviruses enveloped?

A

yes

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18
Q

what kind of capsid do orthomyxoviruses have?

A

helical

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19
Q

hemagglutinin binds to

A

sialic acid receptors on host cell to promote viral entry

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20
Q

influenza is caused by

A

orthomyxoviruses

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21
Q

antigenic shift

A

reassortment of entire genome, shift in phenotype

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22
Q

antigenic shift causes

A

pandemics

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23
Q

antigenic drift

A

point mutations

24
Q

antigenic drift causes

A

epidemics

25
Q

neuraminidase promotes

A

viral progeny release

26
Q

classic influenza presentation

A

fever, cough, sore throat, myalgia

27
Q

oseltamivir, zanamivir

A

NA inhibitors

28
Q

oseltamivir, zanamivir treat which strain of the flu

A

A and B

29
Q

amantidine

A

impairs viral uncoating

30
Q

amantidine is used against what flu strain

A

A

31
Q

paramyxoviruses have what genetic material

A

-sense ss linear RNA

32
Q

are paramyxoviruses enveloped?

A

yes

33
Q

are paramyxoviruses segmented?

A

no

34
Q

virulence factors: paramyxoviruses

A

HA
NA
matrix protein
F protein

35
Q

pavlizimuab

A

RSV PPX in premature infants

36
Q

RSV causes ____ in infants

A

bronchiolitis

37
Q

croup is caused by

A

parainfluenza virus

38
Q

laryngotracheobronchitis

A

croup

39
Q

barking seal like cough and inspiratory stridor

A

croup

40
Q

steeple sign

A

croup

41
Q

prodromal fever with cough, coryza, conjunctivitis, koplik spots

A

measles

42
Q

koplik spots

A

bright red spots with blue white center on buccal mucosa

43
Q

maculopapular rash that starts at the head/neck and spreads down

A

measles

44
Q

Warthin-Finkeldey giant cells

A

measles

45
Q

non-specific prodrome (fever, malaise, headaches, myalgias)

A

mumps

46
Q

parotitis, orchitis

A

mumps

47
Q

aseptic meningitis

A

mumps

48
Q

what genetic material is in rhabdoviruses?

A
  • sense ss linear RNA
49
Q

are rhabdoviruses enveloped?

A

yes

50
Q

are filoviruses enveloped?

A

yes

51
Q

what kind of capsid do filoviruses have?

A

helical

52
Q

what kind of genetic material to filoviruses have

A

-sense linear ssRNA

53
Q

what kind of genetic material do arenaviruses have?

A

+ and - sense circular ssRNA

2 segments

54
Q

what kind of capsid do arenaviruses have?

A

helical

55
Q

what kind of genetic material is in bunyaviruses?

A

-sense circular ssRNA

3 segments

56
Q

is bunyavirus enveloped?

A

yes

57
Q

what kind of capsule does bunyavirus have?

A

helical

IBI Test I (18 decks)

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