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Pharamcology > Sympathomimetics ANS > Flashcards

Sympathomimetics ANS Flashcards

1
Q

What is a catecholamine And what metabolize it

A

A Dihydroxyphenylethylamine derivative 
Chatachol-O-methyltransferase

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2
Q

Name an alpha Agonist That causes mydriasis

A

Phenylephrine

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3
Q

Which Beta agonists drugs are used for reversing bronchospasm

A

Albuterol
isoproterenol
Metaproteranol
Terbutaline

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4
Q

Which type of receptor agonist decreases salt and water secretion into the intestine

A

Alpha two

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5
Q

What are the effects of alpha-one agonists on vascular system

A
  1. Contract vascular smooth muscle
  2. Increase peripheral vascular resistance
  3. Venous pressure
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6
Q

Name alpha-2 agonist effect on vascular system

A

Vasoconstriction

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7
Q

What are the effects of beta - 2 Agonists on the vascular system

A
  1. Reduce arterial tone in skeletal muscle vascular beds 
  2. Reduce Vascular resistance and arterial blood pressure
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8
Q

What are the effects of dopamine on the vascular system

A

Vasodilation in splenic and Renal vascular beds by activating D1 receptors

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9
Q

What is the effect of a pure alpha agonist on heart rate

A

Routinely slows heart rate via baroreceptor reflex

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10
Q

What are the effects of pure beta agonist on heart rate

A

Almost always increases heart rate

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11
Q

Which Adrenoceptor has the greatest effect on vascular resistance

A

Alpha and beta two

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12
Q

Which receptor influences pulse pressure

A

Beta one

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13
Q

Which type of Agonist increases renin secretion 

A

Beta one agonist

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14
Q

Which agonist increases insulin secretion

A

Beta two 

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15
Q

What is the drug of choice for immediate treatment of anaphylactic shock

A

Epinephrine 

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16
Q

Which drugs are used in ADHD

A
  1. Methylphenidate
  2. Amphetamine
  3. methamphetamine
17
Q

Name two alpha agonists used in the eye to reduce conjunctive itching and irritation

A

Tetrahydrozoline
Phenylephrine 

18
Q

Name two alpha-2 agonist used in glaucoma

A

Apraclonidine
Brimonidine

19
Q

Name a drug that can be used for AV block

A

Isoproterenol

20
Q

Name direct acting catecholamines

A
  1. Epinephrine
  2. Norepinephrine
  3. dopamine
  4. isoproterenol
  5. Dobutamine
21
Q

Name non-catecholamine alpha selective agonists

A

Phenylephrine
Methoxamine
Clonidine

22
Q

Name non-catecholamines beta 2 selective agonist

A
  1. Albuterol
  2. terbutaline
  3. metaproterenol
  4. Salmeterol
  5. Formoterol
  6. Indacaterol
  7. Vilanterol
  8. Olodaterol
23
Q

Name indirect acting phenylisoproplamines agonists

A
  1. Amphetamine
  2. methamphetamine
  3. ephedrine
24
Q

What is the effect of adrenaline an anaphylactic shock

A
  1. Cardiac stimulation
  2. increased blood pressure
  3. increased peripheral resistance
  4. decreased mucosal edema
  5. decrease release of mediators from mast cells
  6. antagonist of histamine
25
Q

What are the therapeutic uses of beta two selective Agonists

A
  1. Bronchial asthma
  2. delay premature labour
  3. hyperkalaemia
26
Q

Name the drug Whose main action is on the uterus and prevents premature labour

A

Ritodrine 

27
Q

What are the adverse effects of using beta two agonists 

A
  1. Tremor
  2. Tachycardia
  3. hyperglycaemia
  4. hypokalaemia
28
Q

Name nasal decongestants 

A
  1. Naphazoline
  2. Oxymetazoline
  3. Xylometazoline
  4. Pseudoephedrine
  5. Phenylephrine
29
Q

Name selective alpha-2 agonist

A
  1. Clonidine
  2. alpha methyldopa
  3. tizanidine
  4. Apraclonidine
  5. Brimonidine
30
Q

How do you treat acute intoxication of amphetamine

A
  1. Ascorbic acid to promote excretion
  2. sedatives to control CNS symptoms
  3. sodium nitroprusside for hypertension
31
Q

What are the uses of amphetamine

A
  1. Narcolepsy
  2. ADHD
  3. anorexiant 
32
Q

Which drug causes increased GFR

A

Dopamine

33
Q

What is the function of Fenoldopam

A

D1 agonist 
used in hypertensive emergencies (decreases BP)

34
Q

Name anorectics (anorexiants)

A
  1. Mazindol
  2. Phentermine
  3. Sibutramine
  4. Orlistat
35
Q

Which drug is able to block reflex bradycardia from alpha-1 agonist

A

Atropine

36
Q

What are the contraindications of using Parasympathomimetics

A
  1. COPD
  2. patients with cardiac disease
  3. narrow angle glaucoma

Pharamcology (15 decks)

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