Miscellaneous CNS Flashcards
name the drugs for Alzheimer’s disease
- Cerebral selective anti-cholinesterases: Donepizel, galantamine, rivastigmine, tubocrine 
- Memamtine (NMDA receptor antagonist)
- Ginkgo biloba
What is the mechanism of action of memantine Used in Alzheimer’s
Inhibits glutamate transmission
What Are the uses of Citicoline 
 1. vascular dementia
2. Parkinsonism
3. stroke
What is the mechanism of a action of citicoline
Increases oxygen and blood flow to the brain
What drug is used for dementia of parkinsonism
piribedil
Gingko biloba is caused what side effects
Causes increased risk of bleeding and should be avoided in patients on anticoagulants
What is the action of doxapram
It is a respiratory stimulant. It stimulates peripheral carotid chemo receptors and direct stimulation of respiratory centre
What are the uses and side effects of doxapram
- Used for respiratory depression following general anaesthesia
- Nausea, vomiting, arrhythmias
What is modafinil? What are its uses an actions?
It is a psychostimulant that enhances wakefulness and vigilance. Used in narcolepsy and sleep disorders
Name ADHD stimulant that suppresses appetite and causes weight loss
Methylphenidate
Name the CNS stimulance used for ADHD
- Amphetermine
- dextroamphetamine
- methylphenidate
- Atomoxetine
What is the function of lithium
Lithium reduces motor activity, decreases euphoria, relieves insomnia and stabilizes the mood in patients with bipolar disorder
What are the potassium sparing drugs
Aldosterone antagonist and sodium channel blockers
What are the two drugs that cause nephrogenic diabetes insipidus?
Lithium and tetracycline
